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TAPA1/CD81 Recombinant Rabbit Monoclonal Antibody [SN206-01] (ET1611-87)

Price: Regular price $385.00

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Catalog# ET1611-87

Rabbit Monoclonal to TAPA1/CD81

Tested for

  • WB

  • IF-Cell

  • IHC-P

  • FC

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
This product has been cited in peer reviewed publications, see list HERE

Safety datasheet

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

TAPA1/CD81 Recombinant Rabbit Monoclonal Antibody [SN206-01] (ET1611-87)

Immunogen

Synthetic peptide within human tapa1 / cd81 aa 161-210 / 236.

Host

Rabbit

Positive Control

PC-12 cell lysate, JAR cell lysate, 293, A549, SH-SY5Y, PC-12, human liver tissue, mouse testis tissue, mouse lung tissue, Jurkat.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

SN206-01

RRID

AB_3070067

APPLICATION DILUTION

  • WB

  • 1:2,000

  • IF-Cell

  • 1:100-1:500

  • IHC-P

  • 1:500-1:2,000

  • FC

  • 1:500-1:1000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 26 kDa

Isotype

IgG

TARGET

UNIPROT #

P60033

PROTEIN NAME

TAPA1/CD81

SYNONYMS

26 kDa cell surface protein TAPA 1 antibody;26 kDa cell surface protein TAPA-1 antibody;26 kDa cell surface protein TAPA1 antibody;CD 81 antibody;CD81 antibody;CD81 antigen (target of antiproliferative antibody;1) antibody;CD81 antigen antibody;CD81 molecule antibody;CD81_HUMAN antibody;CVID6 antibody;S5.7 antibody;TAPA 1 antibody;TAPA1 antibody;Target of the antiproliferative antibody;1 antibody;Tetraspanin 28 antibody;Tetraspanin-28 antibody;Tetraspanin28 antibody;Tspan 28 antibody;Tspan-28 antibody;Tspan28 antibody

SEQUENCE SIMILARITIES

Belongs to the tetraspanin (TM4SF) family.

TISSUE SPECIFICITY

Expressed on B cells (at protein level). Expressed in hepatocytes (at protein level). Expressed in monocytes/macrophages (at protein level). Expressed on both naive and memory CD4-positive T cells (at protein level).

POST-TRANSLATIONAL MODIFICATION

Not glycosylated.; Likely constitutively palmitoylated at low levels. Protein palmitoylation is up-regulated upon coligation of BCR and CD9-C2R-CD81 complexes in lipid rafts.

SUBCELLULAR LOCATION

Cell membrane, Basolateral cell membrane.

FUNCTION

CD81, also called TAPA-1, is a type III transmembrane protein that is broadly expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin. CD81 is believed to be involved in both cell growth and signal transduction. It can be present as a multimolecular complex in association with CD37 and/or CD53, or on the surface of B cells in association with CD19, CD21 and/or MHC class II antigens.

CITATIONS

  • Extracellular vesicles carrying proinflammatory factors may spread atherosclerosis to remote locations

  • Exosomes Derived from Pancreatic Cancer Cells Induce Osteoclast Differentiation Through the miR125a-5p/TNFRSF1B Pathway

  • Chen Wei,et al

    EBV + B cell-derived exosomes promote EBV-associated T/NK-cell lymphoproliferative disease immune evasion by STAT3/IL-10/PD-L1 pathway

  • Liu, J., Peng, X., Liu, Y., Hao, R., Zhao, R., Zhang, L., Zhao, F., Liu, Q., Liu, Y., & Qi, Y.

    The Diagnostic Value of Serum Exosomal Has_circ_0000615 for Breast Cancer Patients

  • Liu, J., Peng, X., Yang, Y., Zhang, Y., Han, M., Shi, X., Zheng, J., Li, T., Chen, J., Lv, W., Liu, Y., Qi, Y., Zhang, L., & Liu, Q.

    The value of hsa_circ_0058514 in plasma extracellular vesicles for breast cancer. Frontiers in oncology, 12, 995196.

  • Wang, Y., Qin, W. Y., Wang, Q., Liu, X. N., Li, X. H., Ye, X. Q., Bai, Y., Zhang, Y., Liu, P., Wang, X. L., Zhou, Y. H., Yuan, H. P., & Shao, Z. B.

    Young Sca-1+ bone marrow stem cell-derived exosomes preserve visual function via the miR-150-5p/MEKK3/JNK/c-Jun pathway to reduce M1 microglial polarization

  • Junjiang Liu,et al

    TAM‐Derived Exosomes Promote EMT by Upregulating lncRNA MIR4435‐2HG in Head and Neck Cancer

  • Li, G., He, L., Huang, J., Liu, J., Chen, W., Zhong, J., Wei, T., Li, Z., Zhu, J., & Lei, J.

    miR-142-3p encapsulated in T lymphocyte-derived tissue small extracellular vesicles induces Treg function defect and thyrocyte destruction in Hashimoto's thyroiditis

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