LDHB Rabbit Polyclonal Antibody (0807-1)

UNIPROT #

P07195

PROTEIN NAME

LDHB

SYNONYMS

Epididymis secretory protein Li 281 antibody;HEL S 281 antibody;L lactate dehydrogenase B chain antibody;L-lactate dehydrogenase B chain antibody;Lactate dehydrogenase H chain antibody;LDH B antibody;LDH H antibody;LDH heart subunit antibody;LDH-B antibody;LDH-H antibody;LDHB antibody;LDHB_HUMAN antibody;LDHBD antibody;LDHH antibody;Renal carcinoma antigen NY REN 46 antibody;Renal carcinoma antigen NY-REN-46 antibody;TRG-5 antibody;TRG5 antibody

SEQUENCE SIMILARITIES

Belongs to the LDH/MDH superfamily. LDH family.

SUBCELLULAR LOCATION

Cytoplasm, Membrane, Mitochondrion, Mitochondrion inner membrane.

FUNCTION

Lactate dehydrogenase (LDH) is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. In medicine, LDH is often used as a marker of tissue breakdown as LDH is abundant in red blood cells and can function as a marker for hemolysis. In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor.