Active Caspase-3 Recombinant Rabbit Monoclonal Antibody [SR01-02] (ET1602-47)

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N6-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma

Jujuboside B Inhibits the Proliferation of Breast Cancer Cell Lines by Inducing Apoptosis and Autophagy

Lu Yang,et al

Discovery of Orally Bioavailable Phenyltetrazolium Derivatives for the Acute Treatment and the Secondary Prevention of Ischemic Stroke

Hu, Yeting;Qian, Yucheng;Wei, Jingsun;Jin, Tian;Kong, Xiangxing;Cao, Hongfeng;Ding, Kefeng

The Disulfiram/Copper Complex Induces Autophagic Cell Death in Colorectal Cancer by Targeting ULK1

Li Xinlei,et al

Chidamide triggers pyroptosis in T-cell lymphoblastic lymphoma/leukemia via the FOXO1/GSDME axis

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Phellinus baumii Polyphenol: A Potential Therapeutic Candidate against Lung Cancer Cells

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hnRNPH1 maintains mitochondrial homeostasis by establishing NRF1/DRP1 retrograde signaling under mitochondrial stress

Guo Q, Yu Y, Tang W, Zhou S, Lv X

Matrine exerts an anti‐tumor effect via regulating HN1 in triple breast cancer both in vitro and in vivo

Fan Chengcheng,et al

Natural Product-Inspired Discovery of Naphthoquinone-Furo-Piperidine Derivatives as Novel STAT3 Inhibitors for the Treatment of Triple-Negative Breast Cancer

Leptin Gene Protects Against Cold Stress in Antarctic Toothfish

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Identification of activating transcription factor 6 (ATF6) as a novel prognostic biomarker and potential target in oral squamous cell carcinoma

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Inhibition of AMPK/PFKFB3 mediated glycolysis synergizes with penfluridol to suppress gallbladder cancer growth

Dr Xia Liu,Professor Jianchao Wang

Silencing RRM2 inhibits multiple myeloma by targeting the Wnt/β-catenin signaling pathway

Jun Wang , Wenjia Liang , Xiangwen Wang , Zhao Chen , Lei Jiang

LTBP2 regulates cisplatin resistance in GC cells via activation of the NF-κB2/BCL3 pathway

OTUD1 chemosensitizes triple-negative breast cancer to doxorubicin by modulating P16 expression

A New Fusion Peptide Targeting Pancreatic Cancer and Inhibiting Tumor Growth

Xia, Z., Li, M., Hu, M., Lin, Y., Atteh, L. L., Fu, W., Gao, L., Bai, M., Huang, C., Yue, P., Liu, Y., & Meng, W.

Phosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway

Li, H., Song, D., Liu, Q., Li, L., Sun, X., Guo, J., Li, D., & Li, P.

miR-351 promotes atherosclerosis in diabetes by inhibiting the ITGB3/PIK3R1/Akt pathway and induces endothelial cell injury and lipid accumulation

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Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway

Wang, C., Wei, S., Liu, B., Wang, F., Lu, Z., Jin, M., & Wang, Y.

Maternal consumption of a fermented diet protects offspring against intestinal inflammation by regulating the gut microbiota

Inhibition of STX17–SNAP29–VAMP8 complex formation by costunolide sensitizes ovarian cancer cells to cisplatin via the AMPK/mTOR signaling pathway

Zhao, X. Q., Wan, H. Y., He, S. Y., Qin, H. J., Yu, B., & Jiang, N.

Vitamin D Receptor Genetic Polymorphisms Associate With a Decreased Susceptibility to Extremity Osteomyelitis Partly by Inhibiting Macrophage Apoptosis Through Inhibition of Excessive ROS Production via VDR-Bmi1 Signaling

Ziwei Liang

SAE1 promotes human glioma progression through activating AKT SUMOylation-mediated signaling pathways.

Autonomous metal-organic framework nanorobots for active mitochondria-targeted cancer therapy

Discovery of N-((3S,4S)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1H-pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity

Evodiamine inhibits ESCC by inducing M-phase cell-cycle arrest via CUL4A/p53/p21 axis and activating noxa-dependent intrinsic and DR4-dependent extrinsic apoptosis

Zhang, G., Dai, S., Chen, Y., Wang, H., Chen, T., Shu, Q., Chen, S., Shou, L., & Cai, X.

Aqueous extract of Taxus chinensis var. mairei regulates the Hippo-YAP pathway and promotes apoptosis of non-small cell lung cancer via ATF3 in vivo and in vitro. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 138, 111506.

Dasatinib causes keratinocyte apoptosis via inhibiting high mobility group Box 1-mediated mitophagy

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Development and Verification of Diagnosis Model for Papillary Thyroid Cancer Based on Pyroptosis-Related Genes: A Bioinformatic and in vitro Investigation

Chen, X. B., Zhu, H. Y., Bao, K., Jiang, L., Zhu, H., Ying, M. D., He, Q. J., Yang, B., Sheng, R., & Cao, J.

Bis-isatin derivatives: design, synthesis, and biological activity evaluation as potent dimeric DJ-1 inhibitors. Acta pharmacologica Sinica, 10.1038/s41401-020-00600-5. Advance online publication.

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A structure-based virtual screening identifies a novel MDM2 antagonist in the activation of the p53 signaling and inhibition of tumor growth

Integrated Analysis of mRNA-seq and miRNA-seq to Identify c-MYC, YAP1 and miR-3960 as Major Players in the Anticancer Effects of Caffeic Acid Phenethyl Ester in Human Small Cell Lung Cancer Cell Line

Discovery of Novel 1,2,3,4-Tetrahydrobenzofuro[2,3-c]pyridine Histone Deacetylase Inhibitors for Efficient Treatment of Hepatocellular Carcinoma

Yuanwen Peng,et al

GALNT9 enrichment attenuates MPP+-induced cytotoxicity by ameliorating protein aggregations containing α-synuclein and mitochondrial dysfunction

Cul4 E3 ubiquitin ligase regulates ovarian cancer drug resistance by targeting the antiapoptotic protein BIRC3

Alleviation of doxorubicin-induced cardiomyocyte death through miR-147-y-mediated mitophagy