GDF15 Rabbit Polyclonal Antibody
Catalog# ER1909-46
GDF15 Rabbit Polyclonal Antibody
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WB
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Mouse
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Rat
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unconjugated
Overview
Product Name
GDF15 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
KLH conjugated synthetic peptide derived from human GDF-15: 221-308/308
Species Reactivity
Mouse, Rat
Validated Applications
WB
Molecular Weight
12.5/34 kDa
Positive Control
Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
-
WB
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1:500-1:2,000
Target
Function
Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
Background References
暂无
Subcellular Location
Secreted.
Synonyms
GDF 15 antibody
GDF-15 antibody
Gdf15 antibody
GDF15_HUMAN antibody
Growth differentiation factor 15 antibody
Growth/differentiation factor 15 antibody
Macrophage inhibitory cytokine 1 antibody
MIC 1 antibody
Mic-1 antibody
MIC1 antibody
ExpandImages
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25 ug total protein per lane of various lysates (see on figure) probed with GDF15 polyclonal antibody, unconjugated (ER1909-46) at 1:1,000 dilution and 4℃ overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Products with the same target and pathway
GDF15 Recombinant Rabbit Monoclonal Antibody [JE39-90]
Application: WB
Reactivity: Human
Conjugate: unconjugated
