VP40 Mouse Monoclonal Antibody [F1-B4]
Catalog# HA600042
VP40 Mouse Monoclonal Antibody [F1-B4]
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ELISA
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Zaire ebolavirus
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unconjugated
Overview
Product Name
VP40 Mouse Monoclonal Antibody [F1-B4]
Antibody Type
Mouse Monoclonal Antibody
Immunogen
Synthetic peptide within C-terminal Zaire ebolavirus VP40.
Species Reactivity
Zaire ebolavirus
Validated Applications
ELISA
Conjugation
unconjugated
Clone Number
F1-B4
RRID
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG1
Purification Method
Protein G affinity purified.
Application Dilution
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ELISA
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Use at an assay dependent concentration.
Target
Function
Ebola virus VP40 Antibody is a high quality monoclonal Ebola virus VP40 antibody (also designated Ebola virus VP40 antibody) suitable for the detection of the Ebola virus VP40 protein of Ebola virus origin. Ebola virus VP40 Antibody (FE18) is available as the non-conjugated anti-Ebola virus VP40 antibody. Ebola virus is an enveloped, negative-stranded RNA virus which belongs to the family Filoviridae and has a distinctive morphology similar only to that of Marburg virus, but apparently has no antigenic characteristics of Marburg virus. Ebola virus is one of at least 18 known viruses capable of causing the viral hemorrhagic fever syndrome. Its genome is a nonsegmented RNA strand with seven structural proteins which include the major nucleoprotein (NP), glycoprotein (GP) and L protein, in addition to four other proteins: VP40, VPX, VP30 and VP24. All the proteins are encoded by monocistronic mRNA transcripts complementary to virion RNA. Only GP, the major protein of the surface spikes, is glycosylated.
Background References
1. Pleet ML. et. al. Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction. Front Microbiol. 2016 Nov
Images
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Immobilized VP40 protein at 1 μg/ml overnight at 4℃. Then blocked with 1% BSA for 1 hour at 37℃, and incubated with the primary antibody (HA600042) for 1 hour at 25℃.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"