TCR beta chain Recombinant Mouse Monoclonal Antibody [PSH16-30]
Catalog# HA601535
TCR beta chain Recombinant Mouse Monoclonal Antibody [PSH16-30]
-
FC
-
Mouse
-
unconjugated
Overview
Product Name
TCR beta chain Recombinant Mouse Monoclonal Antibody [PSH16-30]
Antibody Type
Recombinant Mouse Monoclonal Antibody
Species Reactivity
Mouse
Validated Applications
FC
Positive Control
Mouse splenocytes.
Conjugation
unconjugated
Clone Number
PSH16-30
Product Features
Form
Liquid
Concentration
1 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 1% BSA, 0.2% Proclean 950.
Isotype
IgG1
Purification Method
Protein A affinity purified.
Application Dilution
-
FC
-
1:1,000
Target
Function
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.
Background References
1. Dutta A et al. New insights into TCR beta-selection. Trends Immunol. 2021 Aug
2. Li G et al. TCR beta chain repertoire characteristic between healthy human CD4+ and CD8+ T cells. Biosci Rep. 2024 Mar
Subcellular Location
Cell membrane.
UNIPROT
Synonyms
MGC108929 antibody
MGC109620 antibody
MGC116333 antibody
MGC152215 antibody
MGC157076 antibody
MGC159579 antibody
MGC159580 antibody
RATTCB antibody
RATTCBC1 antibody
T cell antigen receptor, beta polypeptide, T cell receptor, beta cluster antibody
ExpandImages
-
Flow cytometric analysis of mouse splenocytes labeling TCR beta chain.
Cells were washed twice with cold PBS and resuspend. Then stained with the primary antibody (HA601535, 1/1,000) (red) compared with Mouse IgG Isotype Control (green). After incubation of the primary antibody at +4℃ for an hour, the cells were stained with a iFluor™ 488 conjugate-Goat anti-Mouse IgG Secondary antibody (HA1125) at 1/1,000 dilution for 30 minutes at +4℃. Unlabelled sample was used as a control (cells without incubation with primary antibody; black).
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"