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APC Conjugated CD127 Recombinant Mouse Monoclonal Antibody [PSH12-76]

Usd: 539

Specification

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Catalog# HA601536F

APC Conjugated CD127 Recombinant Mouse Monoclonal Antibody [PSH12-76]

Application

  • FC

Reactivity

  • Human

Conjugation

  • APC

Overview

Product Name

APC Conjugated CD127 Recombinant Mouse Monoclonal Antibody [PSH12-76]

Antibody Type

Recombinant Mouse Monoclonal Antibody

Species Reactivity

Human

Validated Applications

FC

Target Molecular Weight

Predicted band size: 52 kDa

Positive Control

Human peripheral blood cells.

Conjugation

APC

Clone Number

PSH12-76

Reactivity Data

Tested Tested Tested
Verified (internally validated)
Published Tested
Reported in literature (not internally validated)
Predicted Tested
Predicted reactive (based on sequence homology)
Not recommended Tested
Not recommended (failed internal validation)
FC
human
Tested Tested

Product Features

Form

Liquid

Concentration

1 mg/mL.(The concentration of this product may be batch-dependent)

Storage Instructions

Store at 2-8℃. Avoid freeze.

Storage Buffer

1*PBS (pH7.4), 1% BSA, 0.2% Proclean 950.

Isotype

IgG1

Purification Method

Protein A affinity purified.

Application Dilution

  • FC

  • 1:1,000

Target

Function

Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans is encoded by the IL7R gene. IL7R-α is a type I cytokine receptor and is a subunit of the functional interleukin-7 receptor and thymic stromal lymphopoietin (TSLP) receptors.

Background References

1. Zhang B et al. CD127 imprints functional heterogeneity to diversify monocyte responses in inflammatory diseases. J Exp Med. 2022 Feb

2. Liang KL et al. Circulating IRF8-expressing CD123(+)CD127(+) lymphoid progenitors: key players in human hematopoiesis. Trends Immunol. 2023 Sep

Subcellular Location

Cell membrane; Secreted.

UNIPROT

SwissProt: P16871 Human

Synonyms

CD 127 antibody

CD127 antibody

CD127 antigen antibody

CDw127 antibody

IL 7R alpha antibody

IL 7R antibody

IL-7 receptor subunit alpha antibody

IL-7R subunit alpha antibody

IL-7R-alpha antibody

IL-7RA antibody

Expand

Images

  • Flow cytometric analysis of human peripheral blood cells labeling CD127 (<a href="/products/HA601536F" style="font-weight: bold;text-decoration: underline;">HA601536F</a>, APC).<br /><br />Cells were washed twice with cold PBS and resuspend. Then incubated for 1 hour at +4℃ with CD127 (<a href="/products/HA601536F" style="font-weight: bold;text-decoration: underline;">HA601536F</a>, APC, 1/1,000) compared with Mouse IgG Isotype Control (APC, 1/1,000).

    Flow cytometric analysis of human peripheral blood cells labeling CD127 (HA601536F, APC).

    Cells were washed twice with cold PBS and resuspend. Then incubated for 1 hour at +4℃ with CD127 (HA601536F, APC, 1/1,000) compared with Mouse IgG Isotype Control (APC, 1/1,000).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"