HNRNPM Recombinant Rabbit Monoclonal Antibody [JE64-62] (HA721103)

UNIPROT #

P52272

PROTEIN NAME

HNRNPM

SYNONYMS

CEA receptor antibody;CEAR antibody;DKFZp547H118 antibody;Heterogeneous nuclear ribonucleoprotein M antibody;Heterogeneous nuclear ribonucleoprotein M4 antibody;Heterogenous nuclear ribonucleoprotein M4 antibody;hnRNA binding protein M4 antibody;hnRNP M antibody;Hnrnpm antibody;HNRNPM4 antibody;HNRPM antibody;HNRPM_HUMAN antibody;HNRPM4 antibody;HTGR1 antibody;N acetylglucosamine receptor 1 antibody;NAGR1 antibody

SUBCELLULAR LOCATION

Nucleolus.

FUNCTION

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.