PCPTP1/PTPRQ Recombinant Rabbit Monoclonal Antibody [JE64-84] (HA721118)

UNIPROT #

Q15256

PROTEIN NAME

PCPTP1/PTPRQ

SYNONYMS

Ch-1PTPase antibody;Ch1 PTPase antibody;DKFZp781C1038 antibody;EC PTP antibody;ECPTP antibody;FLJ34328 antibody;MGC131968 antibody;MGC148170 antibody;NC PTPCOM1 antibody;NC-PTPCOM1 antibody;Protein tyrosine phosphatase Cr1PTPase precursor antibody;Protein tyrosine phosphatase NC PTPCOM1 antibody;Protein tyrosine phosphatase PCPTP1 antibody;Protein tyrosine phosphatase receptor type R antibody;Protein-tyrosine phosphatase PCPTP1 antibody;PTP SL antibody;PTPBR7 antibody;PTPRQ antibody;PTPRR antibody;PTPRR_HUMAN antibody;PTPSL antibody;R-PTP-R antibody;Receptor type tyrosine protein phosphatase R antibody;Receptor-type tyrosine-protein phosphatase R antibody

SUBCELLULAR LOCATION

Cell membrane; Perinuclear region.

FUNCTION

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12.