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SLC34A2 Recombinant Rabbit Monoclonal Antibody [PD00-69]

Usd: 385

Specification

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Catalog# HA721200

SLC34A2 Recombinant Rabbit Monoclonal Antibody [PD00-69]

Application

  • IHC-P

Reactivity

  • Human

Conjugation

  • unconjugated

Overview

Product Name

SLC34A2 Recombinant Rabbit Monoclonal Antibody [PD00-69]

Antibody Type

Recombinant Rabbit monoclonal Antibody

Immunogen

Synthetic peptide within N-terminal Human SLC34A2.

Species Reactivity

Human

Validated Applications

IHC-P

Molecular Weight

Predicted band size: 76 kDa

Positive Control

Human lung carcinoma tissue, human ovary carcinoma tissue, human endometrium tissue.

Conjugation

unconjugated

Clone Number

PD00-69

RRID

AB_3072320

Product Features

Form

Liquid

Concentration

1 mg/mL.(The concentration of this product may be batch-dependent)

Storage Instructions

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Isotype

IgG

Purification Method

Protein A affinity purified.

Application Dilution

  • IHC-P

  • 1:200

Target

Function

The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene. May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli.

Background References

1. Vlasenkova R et al. Characterization of SLC34A2 as a Potential Prognostic Marker of Oncological Diseases. Biomolecules. 2021 Dec

2. He J et al. SLC34A2 simultaneously promotes papillary thyroid carcinoma growth and invasion through distinct mechanisms. Oncogene. 2020 Mar

Subcellular Location

Apical cell membrane.

UNIPROT

SwissProt: O95436 Human

Synonyms

Na(+)-dependent phosphate cotransporter 2B antibody

Na(+)/Pi cotransporter 2B antibody

NaPi-2b antibody

NaPi3b antibody

NPT2B_HUMAN antibody

SLC34A2 antibody

Sodium-dependent phosphate transport protein 2B antibody

Sodium-phosphate transport protein 2B antibody

Sodium/phosphate cotransporter 2B antibody

Solute carrier family 34 member 2 antibody

Images

  • Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue with Rabbit anti-SLC34A2 antibody (<a href="/products/HA721200" style="font-weight: bold;text-decoration: underline;">HA721200</a>) at 1/200 dilution.<br /><br />The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH<sub>2</sub>O and PBS, and then probed with the primary antibody (<a href="/products/HA721200" style="font-weight: bold;text-decoration: underline;">HA721200</a>) at 1/200 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

    Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue with Rabbit anti-SLC34A2 antibody (HA721200) at 1/200 dilution.

    The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (HA721200) at 1/200 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • Immunohistochemical analysis of paraffin-embedded human ovary carcinoma tissue with Rabbit anti-SLC34A2 antibody (<a href="/products/HA721200" style="font-weight: bold;text-decoration: underline;">HA721200</a>) at 1/200 dilution.<br /><br />The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH<sub>2</sub>O and PBS, and then probed with the primary antibody (<a href="/products/HA721200" style="font-weight: bold;text-decoration: underline;">HA721200</a>) at 1/200 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

    Immunohistochemical analysis of paraffin-embedded human ovary carcinoma tissue with Rabbit anti-SLC34A2 antibody (HA721200) at 1/200 dilution.

    The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (HA721200) at 1/200 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • Immunohistochemical analysis of paraffin-embedded human endometrium tissue with Rabbit anti-SLC34A2 antibody (<a href="/products/HA721200" style="font-weight: bold;text-decoration: underline;">HA721200</a>) at 1/200 dilution.<br /><br />The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH<sub>2</sub>O and PBS, and then probed with the primary antibody (<a href="/products/HA721200" style="font-weight: bold;text-decoration: underline;">HA721200</a>) at 1/200 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

    Immunohistochemical analysis of paraffin-embedded human endometrium tissue with Rabbit anti-SLC34A2 antibody (HA721200) at 1/200 dilution.

    The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (HA721200) at 1/200 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"