ODF2 Recombinant Rabbit Monoclonal Antibody [JE35-01] (HA721425)

UNIPROT #

Q5BJF6

PROTEIN NAME

ODF2

SYNONYMS

84 kDa outer dense fiber protein antibody;Cancer/testis antigen 134 antibody;Cenexin 1 antibody;Cenexin antibody;Cenexin1 variant 1 antibody;CT134 antibody;FLJ44866 antibody;KKT 4 antibody;KKT4 antibody;MGC111096 antibody;MGC9034 antibody;ODF 2 antibody;ODF 84 antibody;odf2 antibody;ODF2/1 antibody;ODF2/2 antibody;ODF84 antibody;ODFP2_HUMAN antibody;OTTHUMP00000022274 antibody;OTTHUMP00000022275 antibody;Outer dense fiber of sperm tail 2 antibody;Outer dense fiber of sperm tails 2 antibody;Outer dense fiber of sperm tails protein 2 antibody;Outer dense fiber of sperm tails, 84 kD antibody;Outer dense fiber protein 2 antibody;Sperm outer dense fiber major protein 2 antibody;Sperm tail structural protein antibody;Testis specific autoantigen antibody

SUBCELLULAR LOCATION

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cell projection, cilium, microtubule organizing center, centriole, spindle pole, flagellum.

FUNCTION

Outer dense fiber protein 2, also known as cenexin, is a protein that in humans is encoded by the ODF2 gene. The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of this gene; however, not all isoforms and variants have been fully described.