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TMP21 Recombinant Rabbit Monoclonal Antibody [PSH01-41] (HA721679)

Price: Regular price $385.00

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Catalog# HA721679

Rabbit Monoclonal to TMP21

Tested for

  • WB

  • IHC-P

  • IF-Tissue

  • IF-Cell

  • FC

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

TMP21 Recombinant Rabbit Monoclonal Antibody [PSH01-41] (HA721679)

Immunogen

Recombinant protein within human tmp21 aa 1-200 / 219.

Host

Rabbit

Positive Control

HeLa cell lysate, 293T cell lysate, Raji cell lysate, Jurkat cell lysate, HepG2 cell lysate, U-87 MG cell lysate, PC-12 cell lysate, mouse pancreas tissue lysate, rat pancreas tissue lysate, rat liver tissue lysate, human breast tissue, human colon tissue, human liver tissue, mouse pancreas tissue, rat pancreas tissue, HeLa.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH01-41

RRID

AB_3072792

APPLICATION DILUTION

  • WB

  • 1:5,000

  • IHC-P

  • 1:200

  • IF-Tissue

  • 1:200

  • IF-Cell

  • 1:250

  • FC

  • 1:500-1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 25 kDa

Isotype

IgG

TARGET

UNIPROT #

P49755

PROTEIN NAME

TMP21

SYNONYMS

1110014C03Rik antibody;21 kDa transmembrane trafficking protein antibody;21 kDa transmembrane-trafficking protein antibody;MGC102351 antibody;p23 antibody;p24 family protein delta 1 antibody;p24 family protein delta-1 antibody;p24(DELTA) antibody;p24delta antibody;p24delta1 antibody;S31I125 antibody;S31III125 antibody;TMED 10 antibody;Tmed10 antibody;TMEDA_HUMAN antibody;Tmp 21 I antibody;Tmp 21 antibody;Tmp 21 I antibody;Tmp-21-I antibody;Transmembrane emp24 domain containing protein 10 antibody;Transmembrane emp24 domain-containing protein 10 antibody;Transmembrane emp24-like trafficking protein 10 (yeast) antibody;Transmembrane protein Tmp21 antibody;Transmembrane trafficking protein 21kD antibody

SUBCELLULAR LOCATION

Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Golgi apparatus membrane, Golgi apparatus, cis-Golgi network membrane, Golgi apparatus, trans-Golgi network membrane, Cytoplasmic vesicle, secretory vesicle membrane, Cell membrane, Melanosome.

FUNCTION

Transmembrane emp24 domain-containing protein 10 is a protein that in humans is encoded by the TMED10 gene. This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

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