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Biotin Conjugated Rat IFN gamma Recombinant Rabbit Monoclonal Antibody [PSH05-70] (HA722589B)

Price: Regular price $409.00

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Catalog# HA722589B

Rabbit Monoclonal to Rat IFN gamma

Tested for

  • ELISA(Det)

Reacts with

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
Conjugated to Biotin

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Biotin Conjugated Rat IFN gamma Recombinant Rabbit Monoclonal Antibody [PSH05-70] (HA722589B)

Immunogen

Recombinant protein within rat ifn gamma aa 23-156.

Host

Rabbit

Positive Control

Recombinant standard Rat IFN gamma protein (HA210577).

Conjugation

Biotin

Clonality

Monoclonal

Clone Number

PSH05-70

APPLICATION DILUTION

  • ELISA(Det)

  • Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH05-71] to Rat IFN gamma (Capture) (HA722423) and recombinant standard Rat IFN gamma protein (HA210577) as the standard. The reference range value is 30.9-2500 pg/ml.

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% ProClin300.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 17.9 kDa

Isotype

IgG

TARGET

UNIPROT #

P01581

PROTEIN NAME

Rat IFN gamma

SYNONYMS

IF 1 antibody;IFG antibody;IFI antibody;ifn g antibody;IFN gamma antibody;IFN immune antibody;IFN, immune antibody;IFN-gamma antibody;IFNG antibody;IFNG_HUMAN antibody;Immune interferon antibody;Interferon gamma antibody;Type II Interferon antibody

SUBCELLULAR LOCATION

Secreted.

FUNCTION

IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.

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