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Biotin Conjugated Human IL-12B p40 Recombinant Rabbit Monoclonal Antibody [PSH03-04] (HA722629B)

Price: Regular price $409.00

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Catalog# HA722629B

Rabbit Monoclonal to IL-12B p40

Tested for

  • ELISA(Det)

Reacts with

  • Human

  • Dog

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
Conjugated to Biotin

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Biotin Conjugated Human IL-12B p40 Recombinant Rabbit Monoclonal Antibody [PSH03-04] (HA722629B)

Immunogen

Recombinant protein within human il-23a aa 20-189.

Specificity

Human il-12b p40 (psh03-04) rabbit mab detects endogenous levels of il-12b p40.

Host

Rabbit

Positive Control

Recombinant Human IL-23 protein (HA210909).

Conjugation

Biotin

Clonality

Monoclonal

Clone Number

PSH03-04

APPLICATION DILUTION

  • ELISA(Det)

  • Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH03-03] to Human Human IL-23 (Detector) (HA721933) and recombinant Human IL-23 protein (HA210909) as the standard. The reference range value is 37-3000 pg/ml.

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% ProClin300.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 20.7 kDa

Isotype

IgG

TARGET

UNIPROT #

P29460

PROTEIN NAME

IL-12B p40

SYNONYMS

IL 23;IL 23 A;IL 23 subunit alpha;IL 23A;IL 23p19;IL-23 subunit alpha;IL-23-A;IL-23p19;IL12B;IL23;Il23a;IL23A_HUMAN;IL23P19;interleukin 12B;Interleukin 23 alpha subunit p19;Interleukin 23 p19 subunit;interleukin 23 subunit alpha;interleukin 23 subunit p19;interleukin six, G CSF related factor;Interleukin-23 subunit alpha;Interleukin-23 subunit p19;JKA3 induced upon T cell activation;MGC79388;P19;SGRF

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

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