CD105 Recombinant Rabbit Monoclonal Antibody [PSH15-97]
Catalog# HA723802
CD105 Recombinant Rabbit Monoclonal Antibody [PSH15-97]
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FC
-
Human
-
unconjugated
Overview
Product Name
CD105 Recombinant Rabbit Monoclonal Antibody [PSH15-97]
Antibody Type
Recombinant Rabbit monoclonal Antibody
Immunogen
Recombinant protein within human CD105 aa 26-586.
Species Reactivity
Human
Validated Applications
FC
Target Molecular Weight
Predicted band size: 71 kDa
Positive Control
U-937.
Conjugation
unconjugated
Clone Number
PSH15-97
Reactivity Data
| FC | |
|---|---|
| Human |
|
| Mouse | |
| Rat |
Product Features
Form
Liquid
Concentration
1 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 1% BSA, 0.2% Proclean 950.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
-
FC
-
1:1,000
Target
Function
Endoglin (ENG) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. It is also commonly referred to as CD105, END, FLJ41744, HHT1, ORW and ORW1. It has a crucial role in angiogenesis, therefore, making it an important protein for tumor growth, survival and metastasis of cancer cells to other locations in the body.
Background References
1. Oladejo M et al. CD105 in the progression and therapy of renal cell carcinoma. Cancer Lett. 2023 Aug
2. Li L et al. CD105: tumor diagnosis, prognostic marker and future tumor therapeutic target. Clin Transl Oncol. 2022 Aug
Subcellular Location
Cell membrane.
UNIPROT
Synonyms
AI528660 antibody
AI662476 antibody
CD 105 antibody
CD105 antibody
CD105 antigen antibody
EGLN_HUMAN antibody
END antibody
Endoglin antibody
Eng antibody
FLJ41744 antibody
ExpandImages
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☑ Relative expression (RE)
Flow cytometric analysis of LNCaP (left, negative) and U-937 (right, positive) cells labeling CD105.
Cells were washed twice with cold PBS and resuspend. Then stained with the primary antibody (HA723802, 1/1,000) (red) compared with Rabbit IgG Isotype Control (green). After incubation of the primary antibody at +4℃ for an hour, the cells were stained with a iFluor™ 488 conjugate-Goat anti-Rabbit IgG Secondary antibody (HA1121) at 1/1,000 dilution for 30 minutes at +4℃. Unlabelled sample was used as a control (cells without incubation with primary antibody; black).
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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