Luteinizing Hormone beta Recombinant Rabbit Monoclonal Antibody [PD00-78]
Catalog# HA723822
Luteinizing Hormone beta Recombinant Rabbit Monoclonal Antibody [PD00-78]
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IHC-P
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Human
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unconjugated
Overview
Product Name
Luteinizing Hormone beta Recombinant Rabbit Monoclonal Antibody [PD00-78]
Antibody Type
Recombinant Rabbit monoclonal Antibody
Species Reactivity
Human
Validated Applications
IHC-P
Molecular Weight
Predicted band size: 15 kDa
Positive Control
Human pituitary tissue.
Conjugation
unconjugated
Clone Number
PD00-78
Reactivity Data
| IHC-P | |
|---|---|
| Human |
|
| Mouse |
|
| Rat |
|
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
-
IHC-P
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1:8,000
Target
Function
Luteinizing hormone subunit beta also known as lutropin subunit beta or LHβ is a polypeptide that in association with an alpha subunit common to all gonadotropin hormones forms the reproductive signaling molecule luteinizing hormone. In humans it is encoded by the LHB gene. This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and a unique beta subunit (this protein) which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
Background References
1. Przygrodzka E et al. Luteinizing Hormone Regulation of Inter-Organelle Communication and Fate of the Corpus Luteum. Int J Mol Sci. 2021 Sep
2. Lei T et al. Luteinizing Hormone Regulates Testosterone Production, Leydig Cell Proliferation, Differentiation, and Circadian Rhythm During Spermatogenesis. Int J Mol Sci. 2025 Apr
Subcellular Location
Secreted.
UNIPROT
Synonyms
CGB4 antibody
HH23 antibody
hLHB antibody
Interstitial cell stimulating hormone beta chain antibody
Leutropin antibody
LHB antibody
LSH B antibody
LSH beta antibody
Luteinizing hormone beta antibody
Luteinizing hormone beta subunit antibody
ExpandImages
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Immunohistochemical analysis of paraffin-embedded human pituitary tissue with Rabbit anti-Luteinizing Hormone beta antibody (HA723822) at 1/8,000 dilution.
The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (HA723822) at 1/8,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"