ELKS Recombinant Rabbit Monoclonal Antibody [PSH17-33] (HA723916)

UNIPROT #

Q8IUD2

PROTEIN NAME

ELKS

SYNONYMS

Cast 2 antibody;CAST2 antibody;CAZ associated structural protein 2 antibody;Elks antibody;ELKS/RAB6 interacting/CAST family member 1 antibody;ELKS/RAB6-interacting/CAST family member 1 antibody;ERC 1 antibody;ERC protein 1 antibody;ERC-1 antibody;Erc1 antibody;ERC1 protein antibody;KIAA1081 antibody;MGC12974 antibody;RAB6 interacting protein 2 antibody;RAB6-interacting protein 2 antibody;RAB6IP2 antibody;RB6I2_HUMAN antibody

SUBCELLULAR LOCATION

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Membrane, Golgi apparatus membrane, Presynaptic cell membrane, Cell projection, podosome.

FUNCTION

ELKS/RAB6-interacting/CAST family member 1 is a protein that in humans is encoded by the ERC1 gene. The name ELKS is derived from "protein rich in the amino acids E, L, K and S" The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene. ELKS has been reported to direct vesicles with RAB6A to melanosomes.