HRP Conjugated Human FABP4 Recombinant Rabbit Monoclonal Antibody [PSH25-38] - Detector
Overview
Product Name
HRP Conjugated Human FABP4 Recombinant Rabbit Monoclonal Antibody [PSH25-38] - Detector
Antibody Type
Recombinant Rabbit monoclonal Antibody
Immunogen
Recombinant protein within Human FABP4 aa 1-132 (HA211489).
Species Reactivity
Human
Validated Applications
ELISA(Det), ELISA
Positive Control
Recombinant Human FABP4 protein (HA211489).
Conjugation
HRP
Clone Number
PSH25-38
Product Features
Form
Liquid
Concentration
1 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
-
ELISA(Det)
-
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH25-37] to Human FABP4 (Capture) (HA725472) and Recombinant Human FABP4 protein (HA211489) as the standard. The reference range value is 1.95-500 pg/mL.
-
ELISA
-
Use at an assay dependent concentration.
Target
Function
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.
Background References
1. Ohguro H., Watanabe M., Hikage F., Sato T., Nishikiori N., Umetsu A., Higashide M., Ogawa T., Furuhashi M. Fatty Acid-Binding Protein 4-Mediated Regulation Is Pivotally Involved in Retinal Pathophysiology: A Review. Int J Mol Sci 25:7717-7717 (2024).
2. Xu S., Luo J., Wang Y., Chen X. Fatty Acid Binding Protein-4 Silencing Inhibits Ferroptosis to Alleviate Lipopolysaccharide-induced Injury of Renal Tubular Epithelial Cells by Blocking Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Signaling. J Physiol Investig 67:47-56 (2024).
Subcellular Location
Cytoplasm. Nucleus.
UNIPROT
Synonyms
Adipocyte lipid-binding protein antibody
Adipocyte-type fatty acid-binding protein antibody
Fatty acid-binding protein 4 antibody
ALBP antibody
A-FABP antibody
AFABP antibody
FABP4 antibody
Images
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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