Human KSR1, C-His Tag Protein
Catalog# HA210518
Human KSR1, C-His Tag Protein
Product Information
Product name
Human KSR1, C-His Tag Protein
Catalog No.
HA210518
Predicted molecular mass
17.9 kD
Protein construction description
A DNA sequence encoding the human KSR1 protein (Q8IVT5) (Glu 27-Gly 172) was expressed with a His tag at the C-terminus.
Accession
Q8IVT5
Protein construction
Source
E.coli
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Its kinase activity is unsure. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
Products with the same target and pathway
Human ABL1/JTK7/p150, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CDC42, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
