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FOXP3 Recombinant Rabbit Monoclonal Antibody (IRS053)

Price: Regular price $209.00

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Catalog# IRS053

Rabbit Monoclonal to FOXP3

Tested for

  • mIHC

Reacts with

  • Mouse

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

FOXP3 Recombinant Rabbit Monoclonal Antibody (IRS053)

Immunogen

Recombinant protein within human foxp3 aa 101-370.

Host

Rabbit

Positive Control

Mouse spleen tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

APPLICATION DILUTION

  • mIHC

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 47 kDa

Isotype

IgG

TARGET

UNIPROT #

Q99JB6

PROTEIN NAME

FOXP3

SYNONYMS

AIID antibody;DIETER antibody;Forkhead box P3 antibody;Forkhead box protein P3 antibody;FOXP3 antibody;FOXP3_HUMAN antibody;FOXP3delta7 antibody;Immune dysregulation polyendocrinopathy enteropathy X linked antibody;Immunodeficiency polyendocrinopathy enteropathy X linked antibody;IPEX antibody;JM2 antibody;MGC141961 antibody;MGC141963 antibody;OTTHUMP00000025832 antibody;OTTHUMP00000025833 antibody;OTTHUMP00000226737 antibody;PIDX antibody;Scurfin antibody;XPID antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm.

FUNCTION

FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Regulatory T cells generally turn the immune response down. In cancer, an excess of regulatory T cell activity can prevent the immune system from destroying cancer cells. In autoimmune disease, a deficiency of regulatory T cell activity can allow other autoimmune cells to attack the body's own tissues.

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