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Aquaporin 5 Recombinant Monoclonal Antibody

Usd: 208

Specification

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Catalog# IRS090RB

Aquaporin 5 Recombinant Monoclonal Antibody

Application

  • mIHC

Reactivity

  • Mouse

Conjugation

  • unconjugated

Overview

Product Name

Aquaporin 5 Recombinant Monoclonal Antibody

Antibody Type

Recombinant Rabbit monoclonal Antibody

Immunogen

Synthetic peptide within human Aquaporin 5 aa 225-265 / 265.

Species Reactivity

Mouse

Validated Applications

mIHC

Molecular Weight

Predicted band size: 28 kDa

Positive Control

Mouse lung tissue.

Conjugation

unconjugated

Product Features

Form

Liquid

Concentration

Storage Instructions

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Isotype

IgG

Purification Method

Protein A affinity purified.

Application Dilution

  • mIHC

  • 1:100

Target

Function

Aquaporin-5 (AQP-5) is a protein that in humans is encoded by the AQP5 gene. Aquaporin-5 (AQP-5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin-5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.

Background References

1. D\'Agostino C et al. Aquaporin-5 Dynamic Regulation. Int J Mol Sci. 2023 Jan

2. Bystrup M et al. Aquaporin-5 in breast cancer. APMIS. 2022 May

Subcellular Location

Apical cell membrane, Cell membrane, Cytoplasmic vesicle membrane.

UNIPROT

SwissProt: Q9WTY4 Mouse

Synonyms

AQP 5 antibody

AQP-5 antibody

AQP5 antibody

AQP5_HUMAN antibody

Aquaporin 5 antibody

Aquaporin-5 antibody

Images

  • mIHC analysis of mouse lung tissue (Formalin/PFA-fixed paraffin-embedded sections) with Rabbit anti-Aquaporin 5 antibody (<a href="/products/IRS090RB" style="font-weight: bold;text-decoration: underline;">IRS090RB</a>) at 1/100 dilution. The immunostaining was performed with the IRISKitCmTSA Kit (<a href="/products/900808" style="font-weight: bold;text-decoration: underline;">900808</a>). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.

    mIHC analysis of mouse lung tissue (Formalin/PFA-fixed paraffin-embedded sections) with Rabbit anti-Aquaporin 5 antibody (IRS090RB) at 1/100 dilution. The immunostaining was performed with the IRISKitCmTSA Kit (900808). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"