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LY6A Recombinant Rabbit Monoclonal Antibody (IRS166RB)

Price: Regular price $278.00

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Catalog# IRS166RB

Rabbit Monoclonal to LY6A

Tested for

  • mIHC

Reacts with

  • Mouse

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

LY6A Recombinant Rabbit Monoclonal Antibody (IRS166RB)

Immunogen

Synthetic peptide within mouse ly6a aa 41-90 / 134.

Host

Rabbit

Positive Control

Mouse liver tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

APPLICATION DILUTION

  • mIHC

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4C. Store at +4C short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20C long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 14 kDa

Isotype

IgG

TARGET

UNIPROT #

P05533

PROTEIN NAME

LY6A

SYNONYMS

Ly-6A.2/Ly-6E. antibody;Ly-6A.2/Ly-6E.1 antibody;Ly6a antibody;LY6A_MOUSE antibody;Ly6al antibody;Lymphocyte antigen 6A-2/6E-1 antibody;Lymphocyte antigen Ly 6A.2/Ly 6E.1 antibody;SCA-1 antibody;Stem cell antigen 1 antibody;T cell activating protein antibody;T-cell-activating protein antibody;TAP antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The Ly-6 alloantigens represent a family of phosphatidylinositol anchored proteins that play a role in the process of T lymphocyte activation. Ly-6 expression is commonly induced on T and B lymphocytes after activation by mitogens. Ly-6A/E is a phosphatidylinositol-linked transmembrane member of the Ly-6 family that is produced in humans after 4 weeks of age. γ-interferon and TNF regulate Ly-6A/E at the level of transcription and mRNA stabilization in certain thymocytes and T-cells.

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