Myogenin Rabbit Polyclonal Antibody
Catalog# IRS177RB
Myogenin Rabbit Polyclonal Antibody
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mIHC
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Mouse
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unconjugated
Overview
Product Name
Myogenin Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Recombinant protein within human Myogenin aa 1-200.
Species Reactivity
Mouse
Validated Applications
mIHC
Molecular Weight
Predicted band size: 25 kDa
Positive Control
Mouse muscle tissue.
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
Storage Instructions
-15℃ to -25℃/1 year(Do not lower than -25℃)
Storage Buffer
1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
-
mIHC
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1:100
Target
Function
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle.
Background References
1. Khilji S. et. al. Dissecting myogenin-mediated retinoid X receptor signaling in myogenic differentiation. Commun Biol. 2020 Jun
2. Ganassi M. et. al. Myogenin is an essential regulator of adult myofibre growth and muscle stem cell homeostasis. Elife. 2020 Oct
Subcellular Location
Nucleus.
UNIPROT
Synonyms
bHLHc3 antibody
cb553 antibody
Class C basic helix-loop-helix protein 3 antibody
MYF 4 antibody
Myf-4 antibody
MYF4 antibody
MYOG antibody
MYOG_HUMAN antibody
Myogenic factor 4 antibody
Myogenic factor 4 myogenin antibody
ExpandImages
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mIHC analysis of mouse muscle tissue (Formalin/PFA-fixed paraffin-embedded sections) with Rabbit anti-Myogenin antibody (IRS177RB) at 1/100 dilution. The immunostaining was performed with the IRISKitCmTSA Kit (900808). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"