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NeuN Recombinant Antibody - Rat IgG1 (Chimeric) (IRS179RT)

Price: Regular price $278.00

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Catalog# IRS179RT

to NeuN

Tested for

  • mIHC

Reacts with

  • Mouse

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Chimeric Antibody primary

Product Name

NeuN Recombinant Antibody - Rat IgG1 (Chimeric) (IRS179RT)

Immunogen

Synthetic peptide within human neun aa 20-60.

Positive Control

Mouse brain tissue.

Conjugation

Unconjugated

APPLICATION DILUTION

  • mIHC

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4C. Store at +4C short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20C long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 34 kDa

Isotype

IgG1

TARGET

UNIPROT #

Q8BIF2

PROTEIN NAME

NeuN

SYNONYMS

FLJ56884 antibody;FLJ58356 antibody;Fox-1 homolog C antibody;fox1 homolog C antibody;Fox3 antibody;FOX3NeuN antibody;hexaribonucleotide binding protein 3 antibody;HRNBP3 antibody;NEUN antibody;neuronal nuclei antibody;Rbfox3 antibody;RFOX3_HUMAN antibody;RNA binding protein fox-1 homolog 3 antibody;RNA binding protein, fox 1 homolog (C. elegans) 3 antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm.

FUNCTION

Neuronal nuclei (NeuN, Fox-3, RBFOX3) is a nuclear protein expressed in most post-mitotic neurons of the central and peripheral nervous systems. NeuN is not detected in Purkinje cells, sympathetic ganglion cells, Cajal-Retzius cells, INL retinal cells, inferior olivary, and dentate nucleus neurons. This neuronal protein was originally identified by immunoreactivity with a monoclonal antibody also called NeuN. Using MS-analysis, NeuN was later identified as the Fox-3 gene product. Fox-3 contains an RNA recognition motif and functions as a splicing regulator. Fox-3 regulates alternative splicing of NumB, promoting neuronal differentiation during development.

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