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Psg16 Rabbit Polyclonal Antibody

Usd: 315

Specification

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Catalog# R1408-5

Psg16 Rabbit Polyclonal Antibody

Application

  • WB

  • IF-Cell

Reactivity

  • Mouse

Conjugation

  • unconjugated

Overview

Product Name

Psg16 Rabbit Polyclonal Antibody

Antibody Type

Rabbit Polyclonal Antibody

Immunogen

Synthetic peptide within mouse Psg16 aa 346-395 / 395.

Species Reactivity

Mouse

Validated Applications

WB, IF-Cell

Molecular Weight

Predicted band size: 45 kDa

Positive Control

Mouse brain, D3

Conjugation

unconjugated

RRID

AB_3073303

Product Features

Form

Liquid

Concentration

1 mg/mL.(The concentration of this product may be batch-dependent)

Storage Instructions

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Isotype

IgG

Purification Method

Immunogen affinity purified.

Application Dilution

  • WB

  • 1:1,000

  • IF-Cell

  • 1:100-1:200

Target

Function

The murine pregnancy-specific glycoprotein-16 (PSG16; previously brain carcinoembryonic antigen/bCEA) is expressed in the brain, especially in neurons, and has previously been reported to be an MHV receptor. The murine pregnancy-specific glycoproteins (PSGs), which mediate placentation and modulate interactions between the fetus and the maternal immune system, resemble the related carcinoembryonic antigen (CEA) proteins in their extracellular Ig-like domains but are secreted rather than membrane-anchored.

Background References

1. Chen DS, Asanaka M, Yokomori K, Wang F, Hwang SB, Li HP, Lai MM. A pregnancy-specific glycoprotein is expressed in the brain and serves as a receptor for mouse hepatitis virus. Proc Natl Acad Sci U S A. 1995; 92:12095–9.

2. McLellan AS, Fischer B, Dveksler G, Hori T, Wynne F, Ball M, Okumura K, Moore T, Zimmermann W. Structure and evolution of the mouse pregnancy-specific glycoprotein (Psg) gene locus. BMC Genomics. 2005; 6:4.

Subcellular Location

Cell membrane, Cell projection

UNIPROT

SwissProt: Q8K0U8 Mouse

Synonyms

Pregnancy specific glycoprotein 16, Pregnancy-specific glycoprotein 16

Images

  • Western blot analysis on mouse brain cell lysates using anti- Psg16 rabbit polyclonal antibodies.

    Western blot analysis on mouse brain cell lysates using anti- Psg16 rabbit polyclonal antibodies.

  • ICC staining Psg16 in mouse embryonic stem cells D3 (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).

    ICC staining Psg16 in mouse embryonic stem cells D3 (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"