TIMP4 Rabbit Polyclonal Antibody
Catalog# ER65170
TIMP4 Rabbit Polyclonal Antibody
-
WB
-
Human
-
Mouse
-
unconjugated
Overview
Product Name
TIMP4 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Recombinant protein within human TIMP4 aa 1-224.
Species Reactivity
Human, Mouse
Validated Applications
WB
Molecular Weight
Predicted band size: 26 kDa
Positive Control
HAEC cell lysate, HeLa cell lysate, Mouse heart tissue lysate, Mouse brain tissue lysate.
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
2 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
-
WB
-
1:5,000
Target
Function
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene. This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
Background References
1. Zhou L et al. TIMP4 serves as a novel potential prognostic biomarker for oral squamous cell carcinoma. Sci Rep. 2025 Feb
2. Zhou W et al. Defect of TIMP4 Is Associated with High Myopia and Participates in Rat Ocular Development in a Dose-Dependent Manner. Int J Mol Sci. 2023 Nov
Subcellular Location
Secreted.
Synonyms
Metalloproteinase inhibitor 4 antibody
TIMP 4 antibody
TIMP metallopeptidase inhibitor 4 antibody
TIMP-4 antibody
Timp4 antibody
TIMP4_HUMAN antibody
Tissue inhibitor of metalloproteinase 4 antibody
Tissue inhibitor of metalloproteinases 4 antibody
Images
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Western blot analysis of TIMP4 on different lysates with Rabbit anti-TIMP4 antibody (ER65170) at 1/5,000 dilution.
Lane 1: HAEC cell lysate
Lane 2: HeLa cell lysate
Lane 3: Mouse heart tissue lysate
Lane 4: Mouse brain tissue lysate
Lysates/proteins at 20 µg/Lane.
Predicted band size: 26 kDa
Observed band size: 26 kDa
Exposure time: 30 seconds; ECL: K1801;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (ER65170) at 1/5,000 dilution was used in 5% BSA at 4℃ overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1/50,000 dilution was used for 1 hour at room temperature.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Human/Monkey TIMP4 Recombinant Rabbit Monoclonal Antibody [PSH21-50] - BSA and Azide free (Detector)
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TIMP4 Recombinant Rabbit Monoclonal Antibody [PSH20-91] - BSA and Azide free
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Reactivity: Human,Mouse,Rat,Green monkey
Conjugate: unconjugated
