Transferrin Mouse Monoclonal Antibody [D7-D11]
Catalog# M0809-5
Transferrin Mouse Monoclonal Antibody [D7-D11]
-
WB
-
Human
-
unconjugated
Overview
Product Name
Transferrin Mouse Monoclonal Antibody [D7-D11]
Antibody Type
Mouse Monoclonal Antibody
Immunogen
Recombinant protein within human Transferrin aa 20-698.
Species Reactivity
Human
Validated Applications
WB
Target Molecular Weight
75 kDa
Positive Control
Purified human transferrin
Conjugation
unconjugated
Clone Number
D7-D11
RRID
Product Features
Form
Liquid
Concentration
2 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG2b
Purification Method
Protein A affinity purified.
Application Dilution
-
WB
-
1:2,000
Target
Function
Human transferrin is a blood plasma protein for iron ion delivery encoded by the TF gene. The gene coding for transferrin in humans is located in chromosome band 3q21. Transferrin is a glycoprotein, which binds iron very tightly but reversibly. Transferrin contains 2 specific high-affinity Fe(III) binding sites. The affinity of transferrin for Fe(III) is extremely high (1023 M-1 at pH 7.4) but decreases progressively with decreasing pH below neutrality. The metal binding properties of transferrin have a great influence on the biochemistry of plutonium.
Background References
1. McGillivray R.T.A., Mendez E., Sinha S.K., Sutton M.R., Lineback-Zins J., Brew K.; "The complete amino acid sequence of human serum transferrin."; Proc. Natl. Acad. Sci. U.S.A. 79:2504-2508(1982).
2. McGillivray R.T.A., Mendez E., Shewale J.G., Sinha S.K., Lineback-Zins J., Brew K.; "The primary structure of human serum transferrin. The structures of seven cyanogen bromide fragments and the assembly of the complete structure."; J. Biol. Chem. 258:3543-3553(1983).
Sequence Similarity
Belongs to the transferrin family.
Tissue Specificity
Expressed by the liver and secreted in plasma.
Subcellular Location
Secreted
UNIPROT
Synonyms
Apotransferrin antibody
Beta 1 metal binding globulin antibody
Beta-1 metal-binding globulin antibody
DKFZp781D0156 antibody
PRO1400 antibody
PRO1557 antibody
PRO2086 antibody
Serotransferrin antibody
Serotransferrin precursor antibody
Siderophilin antibody
ExpandImages
-
Western blot analysis on purified human transferrin using anti-transferrin Mouse mAb (Cat. # M0809-5).
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Products with the same target and pathway
Transferrin Rabbit Polyclonal Antibody
Application: WB,IHC-P,FC
Reactivity: Human
Conjugate: unconjugated
Transferrin Mouse Monoclonal Antibody [E4-E6]
Application: IF-Cell,IHC-P,FC,WB
Reactivity: Human
Conjugate: unconjugated
