Acetyl-Histone H3 (K27) Mouse Monoclonal Antibody [A6D7] (HA600047)

UNIPROT #

P68431

PROTEIN NAME

Acetyl-Histone H3 (K27)

SYNONYMS

HIST1 cluster, H3J antibody;Histone gene cluster 1, H3 histone family, member E antibody;Histone gene cluster 1, H3G antibody;H3 histone family, member J antibody;HIST1 cluster, H3E antibody;HIST1 cluster, H3I antibody;Histone gene cluster 1, H3C antibody;FLJ92264 antibody;H3 histone family, member A antibody;H3 histone family, member B antibody;H3 histone family, member C antibody;H3 histone family, member D antibody;H3 histone family, member F antibody;H3 histone family, member H antibody;H3 histone family, member I antibody;H3 histone family, member K antibody;H3 histone family, member L antibody;H3 histone family, member T antibody;H3 histone, family 3A antibody;H3.1 antibody;H3.3A antibody;H3/a antibody;H3/b antibody;H3/c antibody;H3/d antibody;h3/f antibody;H3/h antibody;H3/i antibody;H3/j antibody;H3/k antibody;H3/l antibody;H3/t antibody;H31_HUMAN antibody;H3F1K antibody;H3F3 antibody;H3F3A antibody;H3FA antibody;H3FB antibody;H3FC antibody;H3FD antibody;H3FF antibody;H3FH antibody;H3FI antibody;H3FJ antibody;H3FK antibody;H3FL antibody;HIST1 cluster, H3A antibody;HIST1 cluster, H3B antibody;HIST1 cluster, H3C antibody;HIST1 cluster, H3D antibody;HIST1 cluster, H3F antibody;HIST1 cluster, H3G antibody;HIST1 cluster, H3H antibody;HIST1H3A antibody;HIST1H3B antibody;HIST1H3C antibody;HIST1H3D antibody;HIST1H3E antibody;HIST1H3F antibody;HIST1H3G antibody;HIST1H3H antibody;HIST1H3I antibody;HIST1H3J antibody;HIST3H3 antibody;Histone 1, H3a antibody;Histone 1, H3b antibody;Histone 1, H3c antibody;Histone 1, H3d antibody;Histone 1, H3e antibody;Histone 1, H3f antibody;Histone 1, H3g antibody;Histone 1, H3h antibody;Histone 1, H3i antibody;Histone 1, H3j antibody;histone 3, H3 antibody;histone cluster 1 H3 family member a antibody;histone cluster 1 H3 family member b antibody;histone cluster 1 H3 family member c antibody;histone cluster 1 H3 family member d antibody;histone cluster 1 H3 family member e antibody;histone cluster 1 H3 family member f antibody;histone cluster 1 H3 family member g antibody;histone cluster 1 H3 family member h antibody;histone cluster 1 H3 family member i antibody;histone cluster 1 H3 family member j antibody;Histone cluster 1, H3a antibody;Histone cluster 1, H3b antibody;Histone cluster 1, H3c antibody;Histone cluster 1, H3d antibody;Histone cluster 1, H3e antibody;Histone cluster 1, H3f antibody;Histone cluster 1, H3g antibody;Histone cluster 1, H3i antibody;Histone cluster 1, H3j antibody;Histone gene cluster 1, H3 histone family, member A antibody;Histone gene cluster 1, H3 histone family, member B antibody;Histone gene cluster 1, H3 histone family, member C antibody;Histone gene cluster 1, H3 histone family, member D antibody;Histone gene cluster 1, H3 histone family, member F antibody;Histone gene cluster 1, H3 histone family, member G antibody;Histone gene cluster 1, H3 histone family, member H antibody;Histone gene cluster 1, H3 histone family, member I antibody;Histone gene cluster 1, H3 histone family, member J antibody;Histone gene cluster 1, H3A antibody;Histone gene cluster 1, H3B antibody;Histone gene cluster 1, H3D antibody;Histone gene cluster 1, H3E antibody;Histone gene cluster 1, H3F antibody;Histone gene cluster 1, H3H antibody;Histone gene cluster 1, H3I antibody;Histone gene cluster 1, H3J antibody;Histone H 3 antibody;Histone H3.1 antibody;histone H3.1t antibody;Histone H3.2 antibody;Histone H3/a antibody;Histone H3/b antibody;Histone H3/c antibody;Histone H3/d antibody;Histone H3/f antibody;Histone H3/h antibody;Histone H3/i antibody;Histone H3/j antibody;Histone H3/k antibody;Histone H3/l antibody;Histone H3/m antibody;Histone H3/o antibody;H3K27ac antibody

SUBCELLULAR LOCATION

Nucleus, Chromosome.

FUNCTION

Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fibers. Two molecules of each of the four core histones (H2A, H2B, H3 and H4) form the octamer, which is comprised of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Human and mouse Histone H4 are subject to methylation at Lys 20, a modification that may be necessary for select DNA transactions or chromatin state transitions.