CXCR1 Rabbit Polyclonal Antibody
Catalog# ER1906-86
CXCR1 Rabbit Polyclonal Antibody
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WB
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Human
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unconjugated
Overview
Product Name
CXCR1 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CXCR1: 186-280/350
Species Reactivity
Human
Validated Applications
WB
Molecular Weight
40 kDa
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
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WB
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1:500-2000
Target
Function
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
Background References
暂无
Subcellular Location
Cell membrane.
UNIPROT
Synonyms
C C antibody
C C CKR 1 antibody
C-X-C chemokine receptor type 1 antibody
CCCKR1 antibody
CD 181 antibody
CD128 antibody
CD181 antibody
CD181 antigen antibody
CDw128a antibody
Chemokine (C X C motif) receptor 1 antibody
ExpandImages
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Sample:
Lane 1: Human Jurkat cell lysates
Lane 2: Human Raji cell lysates
Primary: Anti-CXCR1 (ER1906-86) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kDa
Observed band size: 61 kDa
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
CXCR1 Rabbit Polyclonal Antibody
Application: WB,IF-Cell
Reactivity: Human
Conjugate: unconjugated
Products with the same target and pathway