IL-5 Rabbit Polyclonal Antibody (HA500081)
Catalog# HA500081
Rabbit Polyclonal to IL-5
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WB
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IF-Cell
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ELISA
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Human
Specifications
Product Type
Rabbit polyclonal primary
Product Name
IL-5 Rabbit Polyclonal Antibody (HA500081)
Immunogen
Synthetic peptide within human il-5 aa 60-110.
Host
Rabbit
Positive Control
LOVO cell lysates, LOVO cells.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:500-1:1,000
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IF-Cell
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1:50-1:200
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ELISA
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1:5,000-1:10,000
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
15 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
IL-5
SYNONYMS
B-cell differentiation factor I antibody;Colony stimulating factor antibody;EDF antibody;Eosinophil differentiation factor antibody;IL-5 antibody;IL5 antibody;IL5_HUMAN antibody;Interleukin 5 (colony stimulating factor, eosinophil) antibody;Interleukin 5 antibody;Interleukin-5 antibody;T Cell Replacing Factor antibody;T-cell replacing factor antibody;TRF antibody
SUBCELLULAR LOCATION
Secreted.
FUNCTION
Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells.Through binding to the interleukin-5 receptor, interleukin 5 stimulates B cell growth and increases immunoglobulin secretion - primarily IgA. It is also a key mediator in eosinophil activation.IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a homodimer.
CITATIONS
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Zhang Dong,et al
TNFSF11/TNFRSF11A Axis Amplifies HDM-Induced Airway Remodeling by Strengthening TGFβ1/STAT3 Action
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WB
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Human
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Mouse
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Citation
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