NCAM1 Recombinant Rabbit Monoclonal Antibody [PSH06-82] (HA722755)

UNIPROT #

P13591

PROTEIN NAME

NCAM1

SYNONYMS

antigen MSK39 identified by monoclonal antibody 5.1H11 antibody;antigen recognized by monoclonal antibody 5.1H11 antibody;CD56 antibody;cell adhesion molecule, neural, 1 antibody;MSK 39 antibody;MSK39 antibody;N-CAM-1 antibody;NCAM 1 antibody;NCAM antibody;NCAM C antibody;NCAM-1 antibody;NCAM1 antibody;NCAM1_HUMAN antibody;NCAMC antibody;Neural cell adhesion molecule 1 antibody;Neural cell adhesion molecule NCAM antibody;OTTHUMP00000235666 antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

Neural cell adhesion molecule (NCAM), also called CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system. Here, the expression of CD56 is mostly associated with, but not limited to, natural killer cells. CD56 has been detected on other lymphoid cells, including gamma delta (γδ) Τ cells and activated CD8+ T cells, as well as on dendritic cells. NCAM has been implicated as having a role in cell–cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory.