Bcl-2 Recombinant Rabbit Monoclonal Antibody [JF104-8] (ET1702-53)

PU.1 negatively regulates tumorigenesis in non-small-cell lung cancer

Wang Yingying,et al

Linderae Radix extract attenuates ulcerative colitis by inhibiting the JAK/STAT signaling pathway

Jiapeng Huang,et al

Dual-tDCS Ameliorates Cerebral Injury and Promotes Motor Function Recovery via cGAS-STING Signaling Pathway in a Rat Model of Ischemic Stroke

Yeong Keng Yoon,et al

Synthesis, evaluation, and mechanism study of novel benzimidazole acylhydrazone derivatives for antitumor activity

Yawen Wang ,et al

Gold (I) complexes bearing EGFR-inhibiting ligands as anti-HCC agents through dual targeting of EGFR and TrxR

Wu Sizhi,et al

Discovery of Momordin Ic that selectively reduces PD-L1 expression in multiple myeloma cells by recruiting SYVN1

Ma Yunhao,et al

New perspective for Calpain-Mediated regulation of meat Quality: Unveiling the impact on mitochondrial pathway apoptosis in post-mortem

Meiqi Wan,et al

Rhein induces apoptosis of AGS and MGC803 cells by regulating the Ras/PI3K/AKT and p38/MAPK signaling pathway

Chen, S., Guo, W., Meng, M., Wu, D., Zhou, T., Wang, L., & Xu, J.

LncRNA SNHG1 Promotes the Progression of Pancreatic Cancer by Regulating FGFR1 Expression via Competitively Binding to miR-497

Liu Yali,et al

Quercetin Promotes Apoptosis of Gastric Cancer Cells through the EGFR-ERK Signaling Pathway

The HSP90 inhibitor KW-2478 depletes the malignancy of BCR/ABL and overcomes the imatinib-resistance caused by BCR/ABL amplification

Jia-Wei Xu,et al

Unleashing AdipoRon's Potential: A Fresh Approach to Tackle Pseudomonas aeruginosa Infections in Bronchiectasis via Sphingosine Metabolism Modulation

Wan Xinwei,et al

Di-n-butyl phthalate induces toxicity in male fetal mouse testicular development by regulating the MAPK signaling pathway

Yue Wang,et al

Carbon dots-cisplatin nano drug delivery system induces the death of oral tongue squamous cell under self-targeting chemical/photodynamic combined therapy

Yin, P., Li, D., Zhao, Q., Cai, M., Wu, Z., Shi, Y., & Su, L.

Gsα deficiency facilitates cardiac remodeling via CREB/ Bmp10-mediated signaling

Chloroquine Intervenes Nephrotoxicity of Nilotinib through Deubiquitinase USP13‐Mediated Stabilization of Bcl‐XL

Tao Jing,et al

A nano-platform combats the "attack" and "defense" of cytoskeleton to block cascading tumor metastasis

Wei, R., Lv, X., Fang, C., Liu, C., Ma, Z., & Liu, K.

Silencing TUFM Inhibits Development of Monocrotaline-Induced Pulmonary Hypertension by Regulating Mitochondrial Autophagy via AMPK/mTOR Signal Pathway

Cheng Yunyun,et al

Screening and Identification of Potentials Molecules Involved in the Radiation Induced Osteoblast Damage

β-arrestin2 deficiency ameliorates S-100-induced autoimmune hepatitis in mice by inhibiting infiltration of monocyte-derived macrophage and attenuating hepatocyte apoptosis

Yang, X., Wei, W., Tan, S., Guo, L., Qiao, S., Yao, B., & Wang, Z.

Identification and verification of HCAR3 and INSL5 as new potential therapeutic targets of colorectal cancer

Li Jingyang,et al

Baicalein is a potential agent targeting glutamine that induces apoptosis by inhibiting the glutamine-mTOR metabolic pathway in lung cancer

Wang Ruixuan,et al

Costunolide ameliorates MNNG-induced chronic atrophic gastritis through inhibiting oxidative stress and DNA damage via activation of Nrf2

Cao, X., Shu, Y., Chen, Y., Xu, Q., Guo, G., Wu, Z., Shao, M., Zhou, Y., Chen, M., Gong, Y., Li, C., Shi, Y., & Bu, H.

Mettl14-Mediated m⁶A Modification Facilitates Liver Regeneration by Maintaining Endoplasmic Reticulum Homeostasis. Cellular and molecular gastroenterology and hepatology, S2352-345X(21)00072-2. Advance online publication.

Chuanlan Liu,et al

Ebeiedinone and peimisine inhibit cigarette smoke extract-induced oxidative stress injury and apoptosis in BEAS-2B cells

A natural product enhances apoptosis via mitochondria/caspase-mediated pathway in HeLa cells.

Xia, Z., Li, M., Hu, M., Lin, Y., Atteh, L. L., Fu, W., Gao, L., Bai, M., Huang, C., Yue, P., Liu, Y., & Meng, W.

Phosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway

Boosting ferroptosis and microtubule inhibition for antitumor therapy via a carrier-free supermolecule nanoreactor

Li, H., Song, D., Liu, Q., Li, L., Sun, X., Guo, J., Li, D., & Li, P.

miR-351 promotes atherosclerosis in diabetes by inhibiting the ITGB3/PIK3R1/Akt pathway and induces endothelial cell injury and lipid accumulation

A novel strategy of integrating network pharmacology and transcriptome reveals antiapoptotic mechanisms of Buyang Huanwu Decoction in treating intracerebral hemorrhage

Huang Yating,et al

Resistance exercise preconditioning prevents disuse muscle atrophy by inhibiting apoptosis and protein degradation via SESN2 in C57BL/6J mice

Wang Jianfeng,et al

Anshen Shumai Decoction inhibits post-infarction inflammation and myocardial remodeling through suppression of the p38 MAPK/c-FOS/EGR1 pathway

Xiaopeng He,et al

Inhibition of Esophageal Squamous Cell Carcinoma Progression by MIR210HG and Activation of the P53 Signaling Pathway to Promote Apoptosis and Autophagy

Yu Qiwen,et al

Nepetoidin B Alleviates Liver Ischemia/Reperfusion Injury via Regulating MKP5 and JNK/P38 Pathway

Tang Xiaolin,et al

GGTLC1 knockdown inhibits the progression of endometrial cancer by regulating the TGF-β/Smad signaling pathway

Autonomous metal-organic framework nanorobots for active mitochondria-targeted cancer therapy

EYE-503: A Novel Retinoic Acid Drug for Treating Retinal Neurodegeneration

Wang J, Xu Z, Lai Y, et al

Silencing of PD-1 combined with EBV-specific killer T cells for the treatment of EBV-associated B lymphoma

Apatinib Inhibits Bladder Cancer through Suppression of the VEGFR2-PI3K-AKT Signaling Pathway as Revealed by Network Pharmacology and in vitro Experimental Verification

Buyang Huanwu decoction ameliorates bleomycin-induced pulmonary fibrosis in rats by attenuating the apoptosis of alveolar type II epithelial cells mediated by endoplasmic reticulum stress

Targeting macrophagic PIM-1 alleviates osteoarthritis by inhibiting NLRP3 inflammasome activation via suppressing mitochondrial ROS/Cl- efflux signaling pathway

Mengli Yang,et al

ADAM8 promotes alcoholic liver fibrosis through the MAPK signaling pathway

Laquinimod Inhibits Microglial Activation, Astrogliosis, BBB Damage, and Infarction and Improves Neurological Damage after Ischemic Stroke

Ding Aoxue,et al

Sesquiterpene lactones from Tithonia diversifolia with ferroptosis-inducing activities

Long, X., Chen, L., Yang, J., Dong, T., Cheng, Q., Wang, W., Zou, Y., Su, Y., Dai, W., Chen, B., & Zhou, X.

Network-based pharmacology and in vitro validation reveal that galangin induces apoptosis in bladder cancer cells by promoting the p53 signaling pathway

Jiang Huangyu,et al

Evodiamine Inhibits the Progression of Esophageal Aquamous Cell Carcinoma via Modulating PI3K/AKT/mTOR Pathway

Ji-Yong Zhou

Rabies virus matrix protein induces apoptosis by targeting mitochondria

Chen Y, Wu Y, Zhou Y, et al

The delaying effect of Qingxin Zishen decoction on ovarian aging: Examining regulation of ovarian mitochondria apoptosis in aged rats

Chaetocin exhibits anticancer effects in esophageal squamous cell carcinoma via activation of Hippo pathway

MicroRNA-579-3p Exerts Neuroprotective Effects Against Ischemic Stroke via Anti-Inflammation and Anti-Apoptosis

Autophagy participates in germline cyst breakdown and follicular formation by modulating glycolysis switch via Akt signaling in newly-hatched chicken ovaries

Yuanwen Peng,et al

GALNT9 enrichment attenuates MPP+-induced cytotoxicity by ameliorating protein aggregations containing α-synuclein and mitochondrial dysfunction

Gang Feng

Tex10 promotes stemness and EMT phenotypes in esophageal squamous cell carcinoma via the Wnt/β-catenin pathway

Li, Y., Li, D., You, L., Deng, T., Pang, Q., Meng, X., & Zhu, B.

dCas9-Based PDGFR-β Activation ADSCs Accelerate Wound Healing in Diabetic Mice through Angiogenesis and ECM Remodeling

Zhang, Y., Li, B. X., Mao, Q. Z., Zhuo, J. C., Huang, H. J., Lu, J. B., Zhang, C. X., Li, J. M., Chen, J. P., & Lu, G.

The JAK-STAT pathway promotes persistent viral infection by activating apoptosis in insect vectors