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FABP4 Recombinant Rabbit Monoclonal Antibody [JM10-99] (ET1703-98)

Price: Regular price $385.00

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Catalog# ET1703-98

Rabbit Monoclonal to FABP4

Tested for

  • WB

  • IF-Cell

  • IHC-Fr

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
This product has been cited in peer reviewed publications, see list HERE

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

FABP4 Recombinant Rabbit Monoclonal Antibody [JM10-99] (ET1703-98)

Immunogen

Synthetic peptide within human fabp4 aa 60-100.

Host

Rabbit

Positive Control

Mouse white adipose tissue lysate, mouse brown adipose tissue lysate, rat white adipose tissue lysate, rat brown adipose tissue lysate, HAEC, MCF-7, A549, PMVEC.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JM10-99

RRID

AB_3070452

APPLICATION DILUTION

  • WB

  • 1:5,000

  • IF-Cell

  • 1:100

  • IHC-Fr:1

  • 100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 15 kDa

Isotype

IgG

TARGET

UNIPROT #

P15090

PROTEIN NAME

FABP4

SYNONYMS

3T3-L1 lipid-binding protein antibody;422/aP2 antibody;A-FABP antibody;adipocyte antibody;Adipocyte lipid binding protein antibody;Adipocyte lipid-binding protein antibody;Adipocyte protein AP2 antibody;Adipocyte-type fatty acid-binding protein antibody;AFABP antibody;ALBP antibody;ALBP/Ap2 antibody;aP2 antibody;Epididymis secretory protein Li 104 antibody;FABP antibody;FABP4 antibody;FABP4_HUMAN antibody;Fatty acid binding protein 4 adipocyte antibody;Fatty acid binding protein 4 antibody;Fatty acid binding protein adipocyte antibody;Fatty acid-binding protein 4 antibody;Fatty acid-binding protein antibody;HEL S 104 antibody;Lbpl antibody;Myelin P2 protein homolog antibody;P15 antibody;P2 adipocyte protein antibody;Protein 422 antibody

SEQUENCE SIMILARITIES

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

SUBCELLULAR LOCATION

Nucleus. Cytoplasm.

FUNCTION

Fatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport, and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21, and encodes a 132-amino acid protein. A-FABP protein comprises approximately 1% of the total cytosolic protein in human adipose tissue.

CITATIONS

  • Liang Ma;Ping Fu

    Inhibition of Fatty Acid–Binding Protein 4 Attenuated Kidney Fibrosis by Mediating Macrophage-to-Myofibroblast Transition

  • GADD45A regulates subcutaneous fat deposition and lipid metabolism by interacting with Stat1

  • Li, L., Tao, S., Guo, F., Liu, J., Huang, R., Tan, Z., Zeng, X., Ma, L., & Fu, P.

    Genetic and pharmacological inhibition of fatty acid-binding protein 4 alleviated inflammation and early fibrosis after toxin induced kidney injury. International immunopharmacology, 96, 107760. Advance online publication.

  • Xu Hui,et al

    Jintiange capsule ameliorates glucocorticoid-induced osteonecrosis of the femoral head in rats by regulating the activity and differentiation of BMSCs

  • Zhiduan Chi,et al

    snRNA-seq of adipose tissues reveals the potential cellular and molecular mechanisms of cold and disease resistance in Mongolian cattle

  • Activation of the PERK-CHOP signaling pathway during endoplasmic reticulum stress contributes to olanzapine-induced dyslipidemia

  • Tizhong Shan

    GADD45α drives brown adipose tissue formation through upregulating PPARγ in mice

  • Liang Ma,Ping Fu

    Pharmacological and genetic inhibition of fatty acid‐binding protein 4 alleviated cisplatin‐induced acute kidney injury

  • Ren, Q., Wang, B., Guo, F., Huang, R., Tan, Z., Ma, L., & Fu, P.

    Natural Flavonoid Pectolinarigenin Alleviated Hyperuricemic Nephropathy via Suppressing TGFβ/SMAD3 and JAK2/STAT3 Signaling Pathways

  • Zhang, P., Tian, L., Bao, J., Li, S., Li, A., Wen, Y., Wang, J., & Jie, Y.

    Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway

  • LKB1 Differently Regulates Adipogenesis in Intramuscular and Subcutaneous Adipocytes through Metabolic and Cytokine-Related Signaling Pathways

  • Liu, Y., Chen, Y., Wang, Y., Jiang, S., Lin, W., Wu, Y., Li, Q., Guo, Y., Liu, W., & Yuan, Q.

    DNA demethylase ALKBH1 promotes adipogenic differentiation via regulation of HIF-1 signaling

  • Chen, W., Xu, Z., You, W., Zhou, Y., Wang, L., Huang, Y., & Shan, T.

    Cold exposure alters lipid metabolism of skeletal muscle through HIF-1α-induced mitophagy

  • Conjugated linoleic acids inhibit lipid deposition in subcutaneous adipose tissue and alter lipid profiles in serum of pigs

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