Biotin Conjugated Human IL-7 Recombinant Rabbit Monoclonal Antibody [PSH03-10]
Overview
Product Name
Biotin Conjugated Human IL-7 Recombinant Rabbit Monoclonal Antibody [PSH03-10]
Antibody Type
Recombinant Rabbit monoclonal Antibody
Immunogen
Recombinant protein within human IL-7 aa 26-177.
Species Reactivity
Human
Validated Applications
ELISA(Det)
Molecular Weight
Predicted band size: 20.2 kDa
Positive Control
Recombinant Human Human IL-7 (HA210595).
Conjugation
Biotin
Clone Number
PSH03-10
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% ProClin300.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
-
ELISA(Det)
-
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH03-09] to Human Human IL-7 (Capture) (HA721937) and recombinant standard Human Human IL-7 (HA210595) as the standard. The reference range value is 8.2-2,000 pg/mL.
Target
Function
IL-7 (Interleukin-7) is a cytokine that plays important roles in lymphocyte differentiation, proliferation, and survival. IL-7 is produced by stromal epithelial cells of the thymus, bone marrow, and intestines. It signals through a receptor complex composed of IL-7 R alpha/CD127 and the Common gamma Chain. gamma c is also a subunit of the receptors for IL-2, -4, -9, -15, and -21. IL-7 contributes to the maintenance of all naïve and memory T cells. It is required for optimal T cell-dendritic cell interaction. In mouse, IL-7 activation of IL-7 R alpha is critical for both T cell and B cell lineage development, while in humans, it is required for T cell but not for B cell development.
Background References
1. Bazdar D.A., Kalinowska M., Panigrahi S., Sieg S.F. Recycled IL-7 Can Be Delivered to Neighboring T Cells. J. Immunol. 194:4698-4704 (2015).
2. Kondo M., Takeshita T., Higuchi M., Nakamura M., Sudo T., Nishikawa S., Sugamura K. Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes. Science 263:1453-1454 (1994).
Subcellular Location
Secreted.
UNIPROT
Synonyms
IL 7 antibody
IL-7 antibody
Il7 antibody
IL7_HUMAN antibody
Interleukin 7 antibody
Interleukin-7 antibody
LP-1 antibody
Lymphopoietin 1 antibody
Images
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Products with the same target and pathway
IL-7 Mouse Monoclonal Antibody [A8B11]
Application: WB
Reactivity: Human
Conjugate: unconjugated
Human IL-7 Recombinant Rabbit Monoclonal Antibody [PSH03-09] - BSA and Azide free (Capture)
Application: ELISA(Cap)
Reactivity: Human
Conjugate: unconjugated
Human IL-7 Recombinant Rabbit Monoclonal Antibody [PSH03-10] - BSA and Azide free (Detector)
Application: ELISA(Det)
Reactivity: Human
Conjugate: unconjugated
