Human GADD45B, N-Twin Strep, C-His, Flag Tag Protein
Catalog# HA210533
Human GADD45B, N-Twin Strep, C-His, Flag Tag Protein
Product Information
Product name
Human GADD45B, N-Twin Strep, C-His, Flag Tag Protein
Catalog No.
HA210533
Predicted molecular mass
24.5 kD
Protein construction description
A DNA sequence encoding the human GADD45B protein (O75293) (Met 1-Arg 160) was expressed with a Twin strep tag at the N-terminus and both His, Flag tag at the C-terminus.
Accession
O75293
Protein construction
Twin Strep
GADD45B (1-160)
His
Flag
Source
E.coli
Purity
>90% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of growth and apoptosis. GADD45B reacts to environmental stresses by mediating activation of stress-responsive MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. In addition, GADD45B participates in the down-regulation of hepatocellular carcinoma (HCC). It may serve as a possible therapeutic target.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
Products with the same target and pathway
Human BAFF/BLyS/TNFSF13B, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL2/GRO beta, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Fas/TNFRSF6/CD95, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CCL21/6Ckine, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Thrombospondin-1/THBS1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human MCP-4/CCL13, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Tau/Tau441 (1-256 Fragment), Tag Free (isoform 2N4R) Protein
Application:
Reactivity: Human
Conjugate:
Human BAFF/TNFSF13B/CD257 Trimer design, N-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CCL19 / MIP-3 beta, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL4/MIP-1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human RANK/TNFRSF11A, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TRAF1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human phosphorylated Tau217 Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 beta/IL1B, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Fas Ligand/TNFSF6, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human BAFFR/TNFRSF13C, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Caspase-3/CASP3, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human HRAS, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human MAPK1/ERK2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human LIGHT/TNFSF14, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TRAF3, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-8/CXCL8 Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TGF-Beta 1 / TGFB1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TNF RI/TNFRSF1A, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human HSPA1A, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human PAI-1/Serpin E1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Cathepsin L / CTSL1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human phosphorylated Tau181 Protein
Application:
Reactivity: Human
Conjugate:
Human beta-NGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Cathepsin D, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human phosphorylated MAPK1/ERK-2 (pT185 and pY187) Protein
Application:
Reactivity: Human
Conjugate:
Human EIF2AK3/PERK, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Caspase-9/CASP9, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Cathepsin S/CTSS, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human LBP, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human phosphorylated Tau231 Protein
Application:
Reactivity: Human
Conjugate:
Human CD14, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD40/TNFRSF5, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Tau/Tau758, C-His (isoform PNS-tau) Protein
Application:
Reactivity: Human
Conjugate:
Human GTPase HRAS, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TNF-alpha, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human HSPA1L, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TNFSF11/RANKL/CD254, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Cathepsin C/CTSC, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human cIAP1/BIRC2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human LTA, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
MTBR-tau243 peptide
Application:
Reactivity:
Conjugate:
Human IKK gamma/NEMO, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human c-Fos, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Beta-NGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human BAFF/TNFSF13B/CD257 Trimer design, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GRO gamma/CXCL3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD40 Ligand/TNFSF5, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human TNF-alpha, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-3R alpha/CD123, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CDC42, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TGF-beta RII, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human MAPK12, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human RAC1, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 beta/IL1B, Tag Free (pro form) Protein
Application:
Reactivity: Human
Conjugate:
Human Granzyme B, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CRKL, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IGFBP3/IBP3, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ICAM-1/CD54, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human MAP4K1/HPK1, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL12/SDF-1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 alpha/IL1A, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human cIAP-2/BIRC3, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Tau/Tau441, C-His (isoform 2N4R) Protein
Application:
Reactivity: Human
Conjugate:
Human VCAM-1 / CD106, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IGF1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45A, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD14, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
