Human CD40/TNFRSF5, C-His Tag Protein
Catalog# HA211232
Human CD40/TNFRSF5, C-His Tag Protein
Product Information
Product name
Human CD40/TNFRSF5, C-His Tag Protein
Catalog No.
HA211232
Predicted molecular mass
21 kD
Protein construction description
A DNA sequence encoding the human CD40/TNFRSF5 (P25942-1) (Glu 21-Arg 193) was expressed with a His tag at the C-terminus.
Accession
P25942-1
Protein construction
CD40/TNFRSF5 (21-193)
His
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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Reactivity: Human
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Human IL-4R, C-His, Tag (ECD) Protein
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Reactivity: Human
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Reactivity: Human
Conjugate:
Human CCL2/MCP1, Tag Free Protein
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Reactivity: Human
Conjugate:
Human CTLA-4, C-His Tag Protein
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Reactivity: Human
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Human CD31/PECAM-1, C-His Tag Protein
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Reactivity: Human
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Human P-Selectin/CD62P, C-His Tag (ECD) Protein
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Reactivity: Human
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Human IL12B/P40, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human PD-1, C-His Tag Protein
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Reactivity: Human
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Human VCAM-1 / CD106, C-His Tag Protein
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Reactivity: Human
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Reactivity: Human
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Human LILRB4/ILT3, C-His, Flag Tag (ECD) Protein
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Reactivity: Human
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Human IL-18 BPa, C-His Tag Protein
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Reactivity: Human
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Human CD63, Tag Free (ECD) Protein
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Reactivity: Human
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Human CD207, C-Flag Tag Protein
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Reactivity: Human
Conjugate:
Human ANPEP/CD13, Tag Free (ECD) Protein
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Reactivity: Human
Conjugate:
Human CXCL1, Tag Free Protein
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Reactivity: Human
Conjugate:
Human B7-DC/PD-L2/CD273, C-Flag Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6R, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45A, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human NCAM1/CD56, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human DPP-4/CD26/DPPIV, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD14, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CYLD, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL2RG/CD132, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human E-Cadherin, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human TIMP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR2/KDR, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-gamma R1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
