Human C-peptide Protein
Catalog# HA211473
Human C-peptide Protein
Product Information
Product name
Human C-peptide Protein
Catalog No.
HA211473
Protein construction description
EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
Accession
P01308-1
Protein construction
C-peptide (57-87)
Formulation
PBS, pH7.4.
Species
Human
Background
The connecting peptide, or C-peptide, is a short 31-amino-acid polypeptide that connects insulin's A-chain to its B-chain in the proinsulin molecule. In the context of diabetes or hypoglycemia, a measurement of C-peptide blood serum levels can be used to distinguish between different conditions with similar clinical features. In the insulin synthesis pathway, first preproinsulin is translocated into the endoplasmic reticulum of beta cells of the pancreas as one polypeptide comprising the regions of the A-chain, C-peptide, B-chain, and signal sequence. The signal sequence is cleaved from the N-terminus of the peptide by a signal peptidase, leaving proinsulin. After proinsulin is packaged into vesicles in the Golgi apparatus (beta-granules), the C-peptide is removed, leaving the A-chain and B-chain bound together by disulfide bonds, that constitute the insulin molecule. C-peptide has virtually no affinity for the insulin receptor, however, it is known to promote the activity of at least two enzymes - the sodium–potassium pump and nitric oxide synthase - downstream of binding to a membrane structure (presumably a G protein-coupled receptor). Nevertheless, the physiological significance of these effects of C-peptide is unresolved.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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Human TRAIL/TNFSF10, C-His Tag Protein
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Human IL-18 R1 / CD218a, C-His Tag Protein
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Human ULBP1/NKG2DL1, C-His Tag Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human IL12RB1, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human ICOS Ligand/B7-H2/ICOSLG, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human FGFR2, C-His Tag Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human ICAM-2/CD102, C-His Tag Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human Kininogen 1, C-His Tag Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
Human IL-13 R alpha 2/IL13RA2, Tag Free (ECD) Protein
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Reactivity: Human
Conjugate:
Human E-Selectin/CD62E, Tag Free (ECD) Protein
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Reactivity: Human
Conjugate:
Human Endoglin/CD105, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD47, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Fas/TNFRSF6/CD95, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human IL-21, Tag Free Protein
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Reactivity: Human
Conjugate:
Human Cathepsin D, C-His Tag Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
Human N-Cadherin, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human IL-17F, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL27, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD155/PVR, Tag Free (ECD) Protein
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Reactivity: Human
Conjugate:
Human CD163, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human M-CSFR/CSF1R/CD115, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human alpha-Synuclein, C-His Tag Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human L-selectin/CD62L, C-His Tag Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human HGF, Tag Free Protein
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Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
Human Fractalkine/CX3CL1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
Human CEACAM-1/CD66a, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD200, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CCL25/TECK, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-8/CXCL8 Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human LDHB, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human LAG-3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD40 Ligand/TNFSF5, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD147/Basigin/EMMPRIN, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Apolipoprotein E/APOE4 (C130R), Tag Free
Application:
Reactivity: Human
Conjugate:
Human IL-10, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IFNA1/IFNA13, C-Tag Protein
Application:
Reactivity: Human
Conjugate:
Human HGF, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human B7-1/CD80, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL5/RANTES, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL26/Eotaxin-3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human 14-3-3 zeta, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL20, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TNF-alpha, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human DKK1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-3R alpha/CD123, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CDC42, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human EPHA2, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human FGF1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human uPAR/PLAUR, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR3/FLT4, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-13, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD28, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human MAPK12, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-alpha/beta R1, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD58/LFA-3, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-21, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human RAC1, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-31, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Flt3 Ligand/FLT3LG, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human SCF/KITLG, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human BST2/Tetherin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD46, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD117/c-Kit, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Tau/Tau758, C-His (isoform PNS-tau) Protein
Application:
Reactivity: Human
Conjugate:
Human TACI/TNFRSF13B, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-20, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NKp46/NCR1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GITR Ligand/TNFSF18, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human SCF/KITLG, Tag Free (26-189) Protein
Application:
Reactivity: Human
Conjugate:
Human NKG2D, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL22 / MDC, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PLGF/PGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD70/CD27 Ligand/TNFSF7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human COL1A2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human WNT7A, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2R alpha, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2RB/CD122, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-gamma, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human 4-1BB/TNFRSF9, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Siglec-7/CD328, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human G-CSF, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 beta/IL1B, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FGF2/b-FGF, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human EGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-10, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human HVEM/TNFRSF14, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human ICAM-1/CD54, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PDGF-B, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-16, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FGF-21, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VEGF121, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TNF RII/TNFRSF1B, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human B7-H3, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-29/IFN-lambda 1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Osteoprotegerin / TNFRSF11B, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD272/BTLA, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human HVEM/TNFRSF14, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human MAPK6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FGF7, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD5, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IP-10/CXCL10, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL12/SDF-1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD27/TNFRSF7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human PPID, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB1/CD85j/ILT2, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GITR/TNFRSF18/AITR, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Leptin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD2, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 alpha/IL1A, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4R, C-His, Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL9, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL2/MCP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CTLA-4, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD31/PECAM-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human P-Selectin/CD62P, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Adiponectin/Acrp30, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL12B/P40, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PD-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Tau/Tau441, C-His (isoform 2N4R) Protein
Application:
Reactivity: Human
Conjugate:
Human VCAM-1 / CD106, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VE-cadherin, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IGF1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB4/ILT3, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-18 BPa, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD63, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD207, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ANPEP/CD13, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human COX5A, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human B7-DC/PD-L2/CD273, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6R, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45A, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human NCAM1/CD56, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Fibronectin/FN1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GH1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human DPP-4/CD26/DPPIV, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PDGF-AA, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD14, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CYLD, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FGF7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL2RG/CD132, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human E-Cadherin, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human TIMP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR2/KDR, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-gamma R1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Interferon alpha-2/IFNA2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Prolactin/PRL, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
