Human CD155/PVR, Tag Free (ECD) Protein

Usd: 379

Specification

100μg

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Catalog# HA211135

Human CD155/PVR, Tag Free (ECD) Protein

Product Information

Product name

Human CD155/PVR, Tag Free (ECD) Protein

Catalog No.

HA211135

Predicted molecular mass

35.4 kD

Protein construction description

A DNA sequence encoding the human CD155/PVR protein (P15151) (Trp 21-Asn 343) was expressed with tag free.

Accession

P15151

Protein construction

CD155/PVR (21-343)

Source

HEK293

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

Human CD155/PVR, Tag Free (ECD) Protein

Usd: 379

Specification

Product Information

Product name

Catalog No.

Predicted molecular mass

Protein construction description

Accession

Protein construction

Source

Purity

Endotoxin

Formulation

Species

Background

Usage guide

Shipping

Storage

Reconstitution

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