Human CCL3/MIP-1, Tag Free Protein

Usd: 159

Specification

20μg

50μg

100μg

Bulk Order Quote | Customization Request

Catalog# HA210901

Human CCL3/MIP-1, Tag Free Protein

Product Information

Product name

Human CCL3/MIP-1, Tag Free Protein

Catalog No.

HA210901

Predicted molecular mass

8.1 kD

Protein construction description

A DNA sequence encoding the human CCL3/MIP-1 protein (P10147) (Ser 24-Ala 92) was expressed with tag free.

Accession

P10147

Protein construction

CCL3/MIP-1 (24-92)

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Chemokine (C-C motif) ligand 3 (CCL3) also known as macrophage inflammatory protein 1-alpha (MIP-1-alpha) is a protein that in humans is encoded by the CCL3 gene. CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes through binding to the receptors CCR1, CCR4 and CCR5. CCL3 produces a monophasic fever of rapid onset whose magnitude is equal to or greater than that of fevers produced with either recombinant human tumor necrosis factor or recombinant human interleukin-1. However, in contrast to these two endogenous pyrogens, the fever induced by MIP-1 is not inhibited by the cyclooxygenase inhibitor ibuprofen and CCL3 may participate in the febrile response that is not mediated through prostaglandin synthesis and clinically cannot be ablated by cyclooxygenase.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

Human CCL3/MIP-1, Tag Free Protein

Usd: 159

Specification

Product Information

Product name

Catalog No.

Predicted molecular mass

Protein construction description

Accession

Protein construction

Source

Bio Activity

Purity

Endotoxin

Formulation

Species

Background

Usage guide

Shipping

Storage

Reconstitution

Products with the same target and pathway

Human IL1RL1/DER4/ST2, C-His (ECD) Protein

Application:

Reactivity: Human

Conjugate:

Human IL-5, C-His Tag Protein

Application:

Reactivity: Human

Conjugate:

Human IL-9, C-Flag Tag Protein

Application:

Reactivity: Human

Conjugate:

Human PRDM1, N-Twin Strep, C-His, Flag Tag Protein

Application:

Reactivity: Human

Conjugate:

Human IL-6, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human CCL17/TARC, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human TRAIL/TNFSF10, C-His Tag Protein

Application:

Reactivity: Human

Conjugate:

Human CD48, C-His Tag Protein

Application:

Reactivity: Human

Conjugate:

Human IL-22, C-His, Flag Tag Protein

Application:

Reactivity: Human

Conjugate:

Human TNF RI/TNFRSF1A, Tag Free (ECD) Protein

Application:

Reactivity: Human

Conjugate:

Human CXCL10, C-Flag Tag Protein

Application:

Reactivity: Human

Conjugate:

Human IL-7, C-His, Flag Tag Protein

Application:

Reactivity: Human

Conjugate:

Human CCL11/Eotaxin, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human IL-2, C-His Tag Protein

Application:

Reactivity: Human

Conjugate:

Human CXCL5, Tag Free Protein

Application: