Human LILRB2/CD85d/ILT4, C-His, Flag Tag (ECD) Protein
Catalog# HA210643
Human LILRB2/CD85d/ILT4, C-His, Flag Tag (ECD) Protein
Product Information
Product name
Human LILRB2/CD85d/ILT4, C-His, Flag Tag (ECD) Protein
Catalog No.
HA210643
Predicted molecular mass
50.4 kD
Protein construction description
A DNA sequence encoding the human LILRB2/CD85d/ILT4 protein (Q8N423) (Gln 22-Val 460) was expressed with both His and Flag tag at the C-terminus.
Accession
Q8N423
Protein construction
LILRB2/CD85d/ILT4 (22-460)
His
Flag
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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