Human ULBP1/NKG2DL1, C-His Tag Protein
Catalog# HA210963
Human ULBP1/NKG2DL1, C-His Tag Protein
Product Information
Product name
Human ULBP1/NKG2DL1, C-His Tag Protein
Catalog No.
HA210963
Predicted molecular mass
23.7 kD
Protein construction description
A DNA sequence encoding the human ULBP1/NKG2DL1 protein (Q9BZM6) (Gly 26-Gly 216) was expressed with a His tag at the C-terminus.
Accession
Q9BZM6
Protein construction
ULBP1/NKG2DL1 (26-216)
His
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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