Human EGFR, C-His Tag Protein
Catalog# HA211104
Human EGFR, C-His Tag Protein
Product Information
Product name
Human EGFR, C-His Tag Protein
Catalog No.
HA211104
Predicted molecular mass
70.4 kD
Protein construction description
A DNA sequence encoding the human EGFR protein (P00533-1) (Leu 25-Ser 645) was expressed with a His tag at the C-terminus.
Accession
P00533-1
Protein construction
EGFR (25-645)
His
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). In many cancer types, mutations affecting EGFR expression or activity could result in cancer. Deficient signaling of the EGFR and other receptor tyrosine kinases in humans is associated with diseases such as Alzheimer's, while over-expression is associated with the development of a wide variety of tumors. Interruption of EGFR signalling, either by blocking EGFR binding sites on the extracellular domain of the receptor or by inhibiting intracellular tyrosine kinase activity, can prevent the growth of EGFR-expressing tumours and improve the patient's condition.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human IL-10, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2, Tag Free Protein
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Reactivity: Human
Conjugate:
Human HVEM/TNFRSF14, Tag Free (ECD) Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
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Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-hFc Tag Protein
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Reactivity: Human
Conjugate:
Human IL-16, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human FGF-21, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VEGF121, Tag Free Protein
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Reactivity: Human
Conjugate:
Human TNF RII/TNFRSF1B, C-His (ECD) Protein
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Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human B7-H3, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
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Human GFAP, Tag Free Protein
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Reactivity: Human
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Human CD272/BTLA, C-His, Flag Tag (ECD) Protein
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human CD2, C-His, Flag Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human IL-1 alpha/IL1A, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human cIAP-2/BIRC3, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Periostin/OSF-2, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4R, C-His, Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human NRG1, C-Flag (176-246) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL9, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL2/MCP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CTLA-4, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD31/PECAM-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human MMP1, C-Flag Protein
Application:
Reactivity: Human
Conjugate:
Human P-Selectin/CD62P, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Beta-2-microglobulin/B2M, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL12B/P40, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PD-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VCAM-1 / CD106, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VE-cadherin, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IGF1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB4/ILT3, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-18 BPa, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD63, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD207, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ANPEP/CD13, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human ACP1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human B7-DC/PD-L2/CD273, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6R, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45A, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Pentraxin 3/PTX3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human MMP-9, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NCAM1/CD56, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Fibronectin/FN1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GH1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human DPP-4/CD26/DPPIV, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PDGF-AA, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD14, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CYLD, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FGF7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL2RG/CD132, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human E-Cadherin, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human TIMP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human MMP2/CLG4A, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR2/KDR, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-gamma R1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Interferon alpha-2/IFNA2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Prolactin/PRL, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Carbonic Anhydrase XII/CA12, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
