Human Bikunin/AMBP, C-His Tag Protein

Usd: 129

Specification

20μg

50μg

100μg

Bulk Order Quote | Customization Request

Catalog# HA211461

Human Bikunin/AMBP, C-His Tag Protein

Product Information

Product name

Human Bikunin/AMBP, C-His Tag Protein

Catalog No.

HA211461

Predicted molecular mass

22.6 kD

Protein construction description

A DNA sequence encoding the human Bikunin/AMBP protein (P02760) (Gly 20-Val 203) was expressed with a His tag at the C-terminus.

Accession

P02760

Protein construction

Bikunin/AMBP (20-203) His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

The AMBP (α-1-Microglobulin/bikunin precursor) gene encodes a protein precursor, known as AMBP, that is cleaved to produce two distinct proteins, designated a-1-Microglobulin and Bikunin. α-1-Microglobulin, also known as protein HC, is a member of the lipocalin superfamily and is secreted mainly in plasma, urine and cerebrospinal fluid. Thought to have reductase/dehydrogenase activity, α-1-Microglobulin exhibits immunosuppressive properties, such as cytokine secretion and inhibition of antigen-induced lymphocyte cell proliferation, and may be involved in the reduction of biological pro-oxidants. The second protein cleavage product, designated Bikunin and also known as inter-α-trypsin inhibitor light chain, ITI-LC or urinary trypsin inhibitor, is a widely expressed protein that is stored in the granules of human connective tissue mast cells. One of many proteins in the Kunitz-type protease inhibitor family, Bikunin prevents autodigestion by exocrine enzymes, such as trypsinogen and chymo-trypsinogen, and plays a role in the antiinflammatory/antiproteinase immune response. Unlike α-1-Microglobulin, Bikunin is implicated in the pathogenesis of a number of renal diseases, such as urolithiasis.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

Human Bikunin/AMBP, C-His Tag Protein

Usd: 129

Specification

Product Information

Product name

Catalog No.

Predicted molecular mass

Protein construction description

Accession

Protein construction

Source

Bio Activity

Purity

Endotoxin

Formulation

Species

Background

Usage guide

Shipping

Storage

Reconstitution

Products with the same target and pathway

Human IL1RL1/DER4/ST2, C-His (ECD) Protein

Application:

Reactivity: Human

Conjugate:

Human CD44, C-His Tag Protein

Application:

Reactivity: Human

Conjugate:

Human Alpha 2 Antiplasmin/SerpinF2, C-HIs Tag Protein

Application:

Reactivity: Human

Conjugate:

Human TAG1/Contactin 2/CNTN2, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human TGF-alpha, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human Procalcitonin/CALCA, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human Thrombospondin-1/THBS1, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human Caspase-1, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human POMC, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human FABP4/A-FABP, C-His Tag Protein

Application:

Reactivity: Human

Conjugate:

Human proBNP, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human TNNI3, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human PAI-1/Serpin E1, C-His Tag Protein

Application:

Reactivity: Human

Conjugate:

Human Cardiotrophin-1/CT-1, Tag Free Protein

Application:

Reactivity: Human

Conjugate:

Human cIAP1/BIRC2, Tag Free Protein

Application: