Human GDF-15, Tag Free Protein
Catalog# HA211526
Human GDF-15, Tag Free Protein
Product Information
Product name
Human GDF-15, Tag Free Protein
Catalog No.
HA211526
Predicted molecular mass
12.7 kD
Protein construction description
A DNA sequence encoding the human GDF-15 protein (Q99988) (Ala 195-Ser 308) was expressed with tag Free.
Accession
Q99988
Protein construction
GDF-15 (195-308)
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
100mM HAC, pH 2.9, 5% trehalose, 5% mannitol
Species
Human
Background
Growth/differentiation factor 15 is a protein that in humans is encoded by the GDF15 gene. GDF15 was first identified as Macrophage inhibitory cytokine-1 or MIC-1. It is a protein belonging to the transforming growth factor beta superfamily. Under normal conditions, GDF15 is expressed in low concentrations in most organs and upregulated because of injury of organs such as liver, kidney, heart and lung. The function of GDF15 is not fully clear but it seems to have a role in regulating inflammatory pathways and to be involved in regulating apoptosis, angiogenesis, cell repair and cell growth, which are biological processes observed in cardiovascular and neoplastic disorders.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in 4mM HCL buffer.
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