Human GLA/alpha-Galactosidase A, C-His Tag Protein
Catalog# HA211251
Human GLA/alpha-Galactosidase A, C-His Tag Protein
Product Information
Product name
Human GLA/alpha-Galactosidase A, C-His Tag Protein
Catalog No.
HA211251
Predicted molecular mass
50.1 kD
Protein construction description
A DNA sequence encoding the human GLA/alpha-Galactosidase A protein (P06280) (Met 1-Leu 429) was expressed with a His tag at the C-terminus.
Accession
P06280
Protein construction
GLA/alpha-Galactosidase A (1-429)
His
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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