Human LDLR/LDL Receptor, Tag Free Protein
Catalog# HA211287
Human LDLR/LDL Receptor, Tag Free Protein
Product Information
Product name
Human LDLR/LDL Receptor, Tag Free Protein
Catalog No.
HA211287
Predicted molecular mass
85.6 kD
Protein construction description
A DNA sequence encoding the human LDLR/LDL Receptor protein (P01130-1) (Ala 22-Arg 788) was expressed with tag free.
Accession
P01130-1
Protein construction
LDLR/LDL Receptor (22-788)
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Binds low density lipoprotein /LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Forms a ternary complex with PGRMC1 and TMEM97 receptors which increases LDLR-mediated LDL internalization.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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