Human Leptin Receptor, C-His Tag (ECD) Protein
Catalog# HA211148
Human Leptin Receptor, C-His Tag (ECD) Protein
Product Information
Product name
Human Leptin Receptor, C-His Tag (ECD) Protein
Catalog No.
HA211148
Predicted molecular mass
95.3 kD
Protein construction description
A DNA sequence encoding the human Leptin Receptor protein (P48357-1) (Phe 22-Asp 839) was expressed with a His tag at the C-terminus.
Accession
P48357-1
Protein construction
Leptin Receptor (22-839)
His
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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