Human NLRP3, Tag Free Protein
Catalog# HA211600
Human NLRP3, Tag Free Protein
Product Information
Product name
Human NLRP3, Tag Free Protein
Catalog No.
HA211600
Predicted molecular mass
28.7 kD
Protein construction description
A DNA sequence encoding the human NLRP3 protein (Q96P20-1) (Lys 134-Ser 374) was expressed with tag free.
Accession
Q96P20-1
Protein construction
NLRP3 (134-374)
Source
E.coli
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
NLR family pyrin domain containing 3 (NLRP3) (previously known as NACHT, LRR, and PYD domains-containing protein 3 [NALP3] and cryopyrin), is a protein that in humans is encoded by the NLRP3 gene located on the long arm of chromosome 1. NLRP3 is expressed predominantly in macrophages and as a component of the inflammasome, detects products of damaged cells such as extracellular ATP and crystalline uric acid. Activated NLRP3 in turn triggers an immune response. Mutations in the NLRP3 gene are associated with a number of organ specific autoimmune diseases.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
Conjugate:
Human GITR/TNFRSF18/AITR, C-Flag Tag (ECD) Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human CD200, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human CD2, C-His, Flag Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human IL-1 alpha/IL1A, C-His, Flag Tag Protein
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Reactivity: Human
Conjugate:
Human IL-4R, C-His, Tag (ECD) Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human CCL2/MCP1, Tag Free Protein
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Reactivity: Human
Conjugate:
Human CTLA-4, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human CD31/PECAM-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human P-Selectin/CD62P, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL12B/P40, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PD-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
Human VE-cadherin, Tag Free (ECD) Protein
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Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
Human CXCL1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human B7-DC/PD-L2/CD273, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6R, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45A, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
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