Human CD21/CR2, C-His Tag Protein
Catalog# HA211498
Human CD21/CR2, C-His Tag Protein
Product Information
Product name
Human CD21/CR2, C-His Tag Protein
Catalog No.
HA211498
Predicted molecular mass
106 kD
Protein construction description
A DNA sequence encoding the human CD21/CR2 protein (P20023-1) (Ile21-Arg 971) was expressed with a His tag at the C-terminus.
Accession
P20023-1
Protein construction
CD21/CR2 (21-971)
His
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. Complement receptor (CR) type 2 (CR2/ CD21) is normally expressed during the immature and mature stages of B cell development. In association with CD19, CD21 plays an important role in enhancing mature B cell responses to foreign antigens.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
Conjugate:
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
Conjugate:
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
Conjugate:
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Human ICAM-1/CD54, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
Human TNF RII/TNFRSF1B, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human B7-H3, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-29/IFN-lambda 1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Osteoprotegerin / TNFRSF11B, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD272/BTLA, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human HVEM/TNFRSF14, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human MAPK6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD5, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IP-10/CXCL10, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL12/SDF-1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD27/TNFRSF7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB1/CD85j/ILT2, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GITR/TNFRSF18/AITR, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD2, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 alpha/IL1A, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4R, C-His, Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL9, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL2/MCP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CTLA-4, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD31/PECAM-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human P-Selectin/CD62P, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL12B/P40, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PD-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VCAM-1 / CD106, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VE-cadherin, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB4/ILT3, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-18 BPa, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD63, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD207, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ANPEP/CD13, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human B7-DC/PD-L2/CD273, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6R, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45A, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human NCAM1/CD56, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human DPP-4/CD26/DPPIV, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD14, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CYLD, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL2RG/CD132, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human E-Cadherin, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human TIMP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR2/KDR, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-gamma R1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
