Human Fas/TNFRSF6/CD95, C-His Tag (ECD) Protein
Catalog# HA211064
Human Fas/TNFRSF6/CD95, C-His Tag (ECD) Protein
Product Information
Product name
Human Fas/TNFRSF6/CD95, C-His Tag (ECD) Protein
Catalog No.
HA211064
Predicted molecular mass
18.4 kD
Protein construction description
A DNA sequence encoding the human Fas/TNFRSF6/CD95 protein (P25445) (Gln 26-Asn 173) was expressed with a His tag at the C-terminus.
Accession
P25445
Protein construction
Fas/TNFRSF6/CD95 (26-173)
His
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Human IL2RG/CD132, C-His Tag (ECD) Protein
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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